GUS | ||
---|---|---|

Baseline risk factors and incident gout | Below median (n=1763) | Above median (n=1761) |

Female sex, n (%) | 901 (51) | 974 (55)^{*} |

Mean age, years (SD) | 55.5 (5.6) | 55.2 (5.6) |

Mean systolic blood pressure, mm Hg (SD) | 127 (16.2) | 127 (15.8) |

Mean diastolic blood pressure, mm Hg (SD) | 76 (9.9) | 76 (9.6) |

Mean BMI, kg/m2 (SD) | 27.9 (4.8) | 28.1 (5.2) |

eGFR, ml/min, n (%) | ||

<60 | 58 (3) | 61 (3) |

60–90 | 1014 (58) | 1010 (58) |

>90 | 691 (39) | 686 (39) |

Alcohol abstinence, n (%) | 993 (56) | 1031 (59) |

Diuretic use, n (%) | 429 (24) | 418 (24) |

Mean baseline serum urate level, µmol/l (SD) | 357 (88) | 376 (87)^{†} |

Incident gout, n (%) | 42 (2.4) | 66 (3.8)^{*} |

Mean and SDs were reported for continuous variables. Frequencies and percentages were reported for categorical variables. The median of the GUS was −0.31 μmol/l.

↵* p<0.05;

↵† p<0.001.

ARIC, Atherosclerosis Risk in Communities Study; BMI, body mass index; eGFR, estimated glomerular filtration rate; GUS, genetic urate score.