Rates of bacterial intracellular infections
| Anti-TNF cohort | On anti-TNF therapy | On anti-TNF therapy+90 days | |
|---|---|---|---|
| Pre 01 January 2006 | |||
| Exposure (pyrs) | 17 816 | 15 302 | 15 999 |
| Total intracellular infection, n | 9 | 7 | 8 |
| Intracellular infection incidence rate/10 000 person years (95% CI) | 5.1 (2.3 to 9.6) | 4.6 (1.8 to 9.4) | 5.0 (2.2 to 9.9) |
| Post 01 January 2006 | |||
| Exposure (pyrs) | 42 573 | 34 110 | 34 988 |
| Total intracellular infection, n | 6 | 4 | 5 |
| Intracellular infection incidence rate/10 000 person years (95% CI) | 1.4 (0.5 to 3.1) | 1.2 (0.3 to 3.0) | 1.4 (0.5 to 3.3) |
| RR comparing infection rate post 01 January 2006 with pre 01 January 2006 (RR (95% CI)) | 0.27 (0.15 to 0.50) | 0.26 (0.20 to 0.34) | 0.29 (0.18 to 0.46) |
*Anti-TNF, antitumour necrosis factor; pyrs, person years of follow-up; RR, rate ratio.