Table 2

Crude incidence rates of tuberculosis and nontuberculous mycobacterial disease (NTM) among the general population and rheumatoid arthritis (RA) patients, Kaiser Permanente Northern California, 2000–2008

Crude incidence rate (95% CI)* tuberculosis NTM
1General KPNC population**2.8 (2.6-3.0)4.1 (3.9-4.4)
2General KPNC population, >50 years old**5.2 (4.7-5.8)11.8 (11.1-12.6)
3Unexposed RA population**8.7 (5.3-13.2)19.2 (14.2-25.0)
4RA Anti-TNF users56 (24-111)105 (59-173)
  • * rate per 100 000 patient years (95% CI).

  • † general KPNC population: 774 tuberculosis and 1145 NTM cases in 27 668 456 person-years.

  • ‡ general KPNC population, ≥50 years old: 396 tuberculosis cases/7 615 385 person-years, 897 NTM cases/7 601 695 person-years.

  • § unexposed RA population: 19 tuberculosis and 42 NTM cases in 219 295 person-years.

  • #RA anti-TNF users: 8 Tuberculosis and 15 NTM cases in 14 286 person-years.

  • ** unexposed to anti-TNF therapy.

  • KPNC, Kaiser Permanente Northern California.