Crude incidence rates of tuberculosis and nontuberculous mycobacterial disease (NTM) among the general population and rheumatoid arthritis (RA) patients, Kaiser Permanente Northern California, 2000–2008
| Crude incidence rate (95% CI)* tuberculosis NTM | ||
|---|---|---|
| 1General KPNC population** | 2.8 (2.6-3.0) | 4.1 (3.9-4.4) |
| 2General KPNC population, >50 years old** | 5.2 (4.7-5.8) | 11.8 (11.1-12.6) |
| 3Unexposed RA population** | 8.7 (5.3-13.2) | 19.2 (14.2-25.0) |
| 4RA Anti-TNF users | 56 (24-111) | 105 (59-173) |
↵* rate per 100 000 patient years (95% CI).
† general KPNC population: 774 tuberculosis and 1145 NTM cases in 27 668 456 person-years.
‡ general KPNC population, ≥50 years old: 396 tuberculosis cases/7 615 385 person-years, 897 NTM cases/7 601 695 person-years.
§ unexposed RA population: 19 tuberculosis and 42 NTM cases in 219 295 person-years.
#RA anti-TNF users: 8 Tuberculosis and 15 NTM cases in 14 286 person-years.
↵** unexposed to anti-TNF therapy.
KPNC, Kaiser Permanente Northern California.