Mothers' characteristics, pregnancy outcome and treatments
| Mothers' characteristics | N=133 |
|---|---|
| Age (years) | 36±5 |
| BMI (kg/m2) | 25±5 |
| Primary APS | 108 (81%) |
| Purely thrombotic APS | 37 (28%) |
| SLE | 18 (14%) |
| Laboratory data | |
| Lupus anticoagulant | 33 (25%) |
| Anticardiolipin IgG/M | 66 (50%)/16 (12%) |
| Anti-β2 glycoprotein-I antibodies G/M | 32 (25%)/25 (19%) |
| Double/triple positivity | 20 (15%)/10 (8%) |
| Treatment before pregnancy | |
| Corticosteroids | 21 (16%) |
| Hydroxychloroquine | 15 (11%) |
| Aspirin | 26 (19%) |
| Treatment during pregnancy | |
| Aspirin and low-molecular weight heparin | 118 (90%) |
| Corticosteroids | 25 (19%) |
| Hydroxychloroquine | 15 (11%) |
| Actual pregnancy outcome | |
| Gestational hypertension/diabetes mellitus | 12 (9%)/14 (11%) |
| Intrauterine growth restriction | 12 (9%) |
| Preeclampsy/hellp syndrome | 3 (2%) |
| Thrombosis | 3 (2%) |
Values are means with SD and numbers with frequencies.
APS, primary antiphospholipid syndrome; BMI, body mass index; SLE, systemic lupus erythematosus.