Table 1

Characteristics of the two cohorts of rheumatoid arthritis (RA) patients and their comparator cohorts under study

Prevalent RAIncident RA
RA patients, n=39 065General population comparators, n=171 965RA patients, n=8077General population comparator, n=37 973
Sex, n (%)
 Women28 392 (71.7)124 706 (71.9)5531 (68.5)25 810 (68.0)
 Men10 980 (27.7)48 711 (28.1)2546 (31.5)12 163 (32.0)
 RF+ at index date, n (%)31 882 (81.6)NA5397 (66.8)NA
 Mean (SD) age at index date61.6 (14.3)60.4 (14.1)57.6 (15.3)57.3 (15.3)
Quartiles of age, n (%)
 16–529111 (23.3)43 727 (25.4)2618 (32.4)12 644 (33.3)
 53–6210 126 (25.9)46 646 (27.1)2173 (26.9)10 228 (26.9)
 63–719419 (24.1)41 694 (24.3)1695 (21.0)7848 (20.7)
 72–9410 409 (26.7)39 898 (23.2)1591 (19.7)7253 (19.1)
Age at first event (mean, SD)
 Ischaemic stroke75.2 (8.9)74.3 (9.3)74.6 (10.0)75.3 (9.0)
 Haemorrhagic stroke72.4 (10.8)70.9 (10.2)73.0 (9.3)71.7 (11.5)
 Median (IQR) duration of RA at index date5 (2–12) yearsNA169 (111–244) daysNA
N (%) individuals excluded with events prior to index date
 Ischaemic stroke1193 (3.1)4577 (2.7)129 (1.6)829 (2.2)
 Haemorrhagic stroke279 (0.7)1202 (0.7)38 (0.5)229 (0.6)
Median (IQR) follow-up in years
 Haemorrhagic stroke3.2 (1.7–4.1)3.4 (1.8–4.2)5.0 (2.6–8.1)5.0 (2.5–8.1)
 Ischaemic stroke3.2 (1.7–4.1)3.3 (1.8–4.2)5.0 (2.5–8.1)4.9 (2.5–8.1)
  • Years since first entry with RA into the Patient Register, which due to truncation is an underestimate of duration of the true clinical disease.

  • Days since symptom onset.