Effect of recommendation adherence on radiographic progression and disability
| One additional erosion at 1 year n=684* | HAQ score ≥1 at 2 years n=640* | |||
|---|---|---|---|---|
| OR (95% CI) | p Value | OR (95% CI) | p Value | |
| Unadjusted | 1.79 (1.11 to 2.89) | 0.02 | 3.01 (1.70 to 5.33) | 0.0002 |
| Adjusted for confounding factors† and centre | 1.94 (1.09 to 3.45) | 0.03 | 2.55 (1.31 to 4.96) | 0.009 |
| Adjusted for propensity score | 1.83 (1.10 to 3.05) | 0.02 | 2.28 (1.25 to 4.18) | 0.007 |
| Adjusted for propensity score, confounding factors† and centre | 1.98 (1.08 to 3.62) | 0.03 | 2.36 (1.17 to 4.67) | 0.02 |
Mixed logistic regression with confounding factors as fixed effects and treatment centre as a random effect.
↵* 684 patients with a calculated propensity score among the 725 patients with the radiographic progression outcome available; 640 patients with a calculated propensity score among the 679 patients with the disability outcome available.
↵† Confounding factors included:
for radiographic progression: age, sex and erosions score at baseline.
for HAQ: age, sex and HAQ score at baseline.
HAQ, health assessment questionnaire.