Table 5

Characteristics of children with neurodevelopmental abnormalities

CaseMother's ageAPS featuresPregnancy outcomePregnancy treatmentGestational age (weeks)SexBirth weight (g)Clinical featuresAPL
132Obstetrical (IUGR/IUD)Gestational diabetesLWMH38M2790AutismNegative
223Obstetrical (RFL)LWMH36M2500Hyperactive behaviourNegative at birth; ACL IgG 12 U at 2 years
344Obstetrical (RFL)Gestational diabetesLWMH-aspirin37F2900Feeding disorders, language delay, growth failureNegative at birth; transient anti-β2GPI IgG 3–9 months
433Obstetrical (IUGR/IUD)IUGRLWMH37F1570Axial hypotony, psychomotor delayNegative
  • ACL, anticardiolipin antibodies; anti-β2GPI, anti-β2 glycoprotein-I antibodies; APL, antiphospholipid antibodies; APS, antiphospholipid syndrome; F, female; IUD, intrauterine fetal death; IUGR, intrauterine growth restriction; LWMH, low-weight molecular heparin; M, male; RFL, recurrent fetal loss.