Table 2

Characteristics of cumulative NP syndromes incorporating attribution models A and B over the study period in patients with SLE

NP events regardless of attribution
n%NP events due to SLE (model A)NP events due to SLE (model B)NP events due to non-SLE causes
Headache65748.400657
Mood disorders21315.73373140
Seizure disorder916.7597813
Anxiety disorder705.20070
Cerebrovascular disease705.228682
Cognitive dysfunction614.5123526
Polyneuropathy443.2162024
Acute confusional state332.416267
Mononeuropathy272.014270
Psychosis231.710221
Cranial neuropathy241.820204
Movement disorder110.8483
Myelopathy131.07121
Aseptic meningitis80.6553
Demyelinating syndrome60.4160
Autonomic disorder20.2220
Plexopathy10.1001
Guillain–Barre syndrome20.2220
Myasthenia gravis20.2020
Total1358229406952
% among 1358 NP events16.929.970.1
  • The attribution of NP events to SLE was determined using two attribution models: (1) attribution model A: NP events that had their onset within the enrolment window and had no exclusions or associations and were not one of the NP events identified by Ainiala12 were attributed to SLE; (2) attribution model B: NP events that had their onset within 10 years of the diagnosis of SLE and were still present within the enrolment window and had no exclusions and were not one of the NP events identified by Ainiala12 were attributed to SLE.

  • NP, neuropsychiatric; SLE, systemic lupus erythematosus.