Table 2

Agreement between classification of disease activity (low, moderate and high) according to the MBDA score and DAS28-CRP

DAS28-CRP
Baseline visit6-Month visitCombination (baseline and 6 months)
MBDA scoreLowModerateHighLowModerateHighLowModerateHigh
Low013932945
Moderate0857747159
High01540241021950
κ (95% CI)0.23 (−0.03 to 0.48)0.32 (0.11 to 0.53)0.34 (0.19 to 0.49)
Weighted κ (95% CI)0.20 (0.01 to 0.39)0.39 (0.02 to 0.76)0.41 (0.21 to 0.61)
  • Counts indicate the number of patients in each disease activity category.

  • Low, MBDA score ≤29, DAS28-CRP ≤2.7; moderate, MBDA score 30–44, DAS28-CRP 2.7–4.1; high, MBDA score >44, DAS28-CRP >4.1.

  • MBDA, multi-biomarker disease activity; DAS28-CRP, disease activity score based on 28 joints-C reactive protein.