Table 1

Patient demographic and baseline characteristics in the ITT population

GO-ON (n=217)Hyalgan (n=209)
Age (years)67.2±7.866.1±8.1
Women, n (%)135 (62%)134 (64%)
BMI (kg/m2)28.0±3.027.7±3.1
Kellgren and Lawrence, n (%)
Grade II101 (46%)113 (54%)
Grade III116 (54%)96 (46%)
WOMAC index scores (0–100 scale)
Pain subscale47.5±14.348.8±14.9
Stiffness subscale46.4±20.848.5±19.7
Function subscale48.7±17.149.3±16.4
Total index48.2±15.849.1±5.3
Global knee pain VAS (0–100 mm)62.1±13.064.2±13.1
Lequesne index of severity (0–24 points)11.2±2.911.2±3.0
PGA VAS (0–100 mm)48.4±18.147.3±17.7
ICOAP total (0–100 scale)46.4±16.748.2±17.4
ICOAP constant (0–100 scale)43.2±18.444.8±19.6
ICOAP intermittent (0–100 scale)49.2±17.051.0±17.3
  • Data are mean±SD unless otherwise indicated.

  • BMI, body mass index; ICOAP, index of intermittent and constant osteoarthritis pain; ITT, intention-to-treat; PGA, patient global assessment; VAS, visual analogue scale; WOMAC, Western Ontario and McMaster Universities.