Antibody and smoking analysed in relation to socio-economic status | Negative | Positive | OR (95% CI) | RERI (95% CI) | Deviation from additivity p | Deviation from multiplicity p |
---|---|---|---|---|---|---|
RF and smoking | ||||||
Never smoked/affluent | 324 | 779 | 1 | 0.3 (0.0 to 0.7) | 0.06 | 0.10 |
Never smoked/deprived | 248 | 568 | 0.98 (0.80 to 1.20) | |||
Ever smoked/affluent | 314 | 884 | 1.17 (0.97 to 1.42) | |||
Ever smoked/deprived | 320 | 1078 | 1.44 (1.19 to 1.74) | |||
ACPA and smoking | ||||||
Never smoked/affluent | 239 | 537 | 1 | 0.3 (−0.1 to 0.7) | 0.20 | 0.06 |
Never smoked/deprived | 220 | 407 | 0.84 (0.66 to 1.07) | |||
Ever smoked/affluent | 224 | 653 | 1.32 (1.05 to 1.66) | |||
Ever smoked/deprived | 251 | 804 | 1.52 (1.21 to 1.90) |
Socioeconomic status was categorised into affluent (Townsend<population median) and deprived (Townsend>population median). Bold typeface are used for results significant at the 5% level. Adjusted for gender, period of birth and cohort/centre.
ACPA, anticitrullinated peptide antibody; RERI, RR due to interaction; RF, rheumatoid factor.