Association of NSAIDs intake with radiographic spinal progression (mSASSS change ≥2 over 2 years) in patients with AS and non-radiographic axial SpA in the multivariate logistic regression analysis
| AS (n=88) | Non-radiographic axial SpA (n=76) | |||
|---|---|---|---|---|
| Parameters | OR (95% CI) | p Value | OR (95% CI) | p Value |
| NSAID intake index over 2 years, >50 vs ≤50 | 0.15 (0.02 to 0.96) | 0.045 | 0.60 (0.06 to 6.61) | 0.679 |
| Syndesmophytes at baseline, present vs not present | 6.80 (1.78 to 25.95) | 0.005 | 15.4 (2.59 to 91.7) | 0.003 |
| CRP at baseline, >6 vs ≤6 mg/l | 1.34 (0.37 to 4.93) | 0.656 | 0.37 (0.03 to 4.36) | 0.432 |
| Smoking status at baseline, present vs not present | 3.45 (0.97 to 12.23) | 0.055 | 1.01 (0.14 to 7.26) | 0.989 |
| R-square=0.289 | R-square=0.268 | |||
AS, ankylosing spondylitis; CRP, C reactive protein; mSASSS, modified Stoke Ankylosing Spondylitis Spine Score; NSAID, non-steroidal anti-inflammatory drug; SpA, spondyloarthritis.