Table 1

Presentation of some baseline data of randomly selected clinical trials and calculation of the average duration that each disease modifying antirheumatic drug (DMARD) was employed

StudyYear of publicationDisease durationNo. of DMARDsMean years/DMARDRadiographic score
RAPID 1820086.22.32.7∼38 (vdHTSS)
RAPID 2920096.02.22.7∼44 (vdHTSS)
OPTION1120087.52.53.0ND
DANCER13200610.43.43.1ND
LITHE1020119.32.63.6∼29 (GTSS) (≅50 vdHTSS)
TOWARD1220089.82.63.8ND
TOTAL8.22.63.2∼38
  • ≅ rough estimation, detailed calculation difficult due to differences in scoring of individual joints and total sum.

  • GTSS, Genant-modified total Sharp score; ND, not done; vdHTSS, van der Heijde-modified total Sharp score.