Table 5

Numbers of adverse events reported during the first 4 months of treatment with MTX and a tapered high dose of prednisone

Numbers of adverse events
Gastrointestinal symptoms98
Nausea47/98
Liver enzyme elevations45
Infectious80
Upper airway tract26/80
Gastrointestinal18/80
Skin/mucosa infection8/80
Pneumonia9/80
Urinary tract infection7/80
Influenza/fever7/80
Skin/mucosa75
Hair loss19/75
Rash16/75
Stomatitis9/75
Central nervous system73
Headache18/73
Dizziness11/73
Mood disorders21/73
Cardiovascular45
Hypertension20/45
Metabolic21
Pulmonary21
Urogenital8
Haematological5
  • MTX, methotrexate.