Summary of inter-rater reproducibility analysis
| Tophi locations | Reader 1 volume (cm3) | Reader 2 volume (cm3) | Difference (cm3) | 95% CI for difference (cm3) | p Value | Average % difference (SD) | Intraclass correlation coefficient | 95% CI for coefficient |
|---|---|---|---|---|---|---|---|---|
| All locations (n=40) | ||||||||
| Mean (SD) | 2.45 (4.46) | 2.45 (4.46) | 0.00* (0.02) | (−0.01 to 0.01) | 0.86 | 1% (3%) | 1.00 | (1.00 to 1.00) |
| Median | 0.78 | 0.78 | 0.00 | |||||
| Range | (0.06–18.70) | (0.06–18.74) | (−0.05–0.08) | |||||
| Feet/ankles (n=22) | ||||||||
| Mean (SD) | 1.43 (2.12) | 1.43 (2.11) | 0.00* (0.02) | (−0.01 to 0.01) | 0.70 | 2% (4%) | 1.00 | (1.00 to 1.00) |
| Median | 0.64 | 0.67 | 0.00 | |||||
| Range | (0.06–8.74) | (0.06–8.75) | (−0.05–0.08) | |||||
| Elbows/knees (n=12) | ||||||||
| Mean (SD) | 5.10 (7.11) | 5.11 (7.12) | 0.00* (0.02) | (−0.01 to 0.01) | 0.39 | 1% (1%) | 1.00 | (1.00 to 1.00) |
| Median | 1.1 | 1.09 | 0.00 | |||||
| Range | (0.07–18.70) | (0.07–18.74) | (−0.04–0.03) | |||||
| Hand/wrist (n=6) | ||||||||
| Mean (SD) | 0.90 (0.78) | 0.90 (0.78) | 0.00* (0.00) | (−0.01 to 0.00) | 0.36 | 0% (0%) | 1.00 | (1.00 to 1.00) |
| Median | 0.84 | 0.84 | 0.00 | |||||
| Range | (0.12–1.98) | (0.12– 1.98) | (−0.01–0.00) | |||||
↵* Average difference refers to bias.