Table 3

Cross-tabulation of disease activity state classification for DAS28, CDAI and RAPID3 indices calculated using PTGL and GH and associated agreement statistics

Index based on PTGL*
RemissionLowModerateHighAbsolute agreementκ statistics
Index based on GH*DAS28
 Remission1141 (16.26)85 (1.21)9 (0.13)0 (0)
 Low112 (1.6)520 (7.41)109 (1.55)0 (0)
 Moderate17 (0.24)146 (2.08)2401 (34.22)183 (2.61)
 High0 (0)0 (0)134 (1.91)2166 (30.87)88.76%0.84
CDAI
 Remission730 (10.4)104 (1.48)5 (0.07)0 (0)
 Low169 (2.41)1421 (20.25)153 (2.18)0 (0)
 Moderate10 (0.14)207 (2.95)1846 (26.31)116 (1.65)
 High0 (0)0 (0)90 (1.28)2172 (30.96)87.92%0.83
RAPID3
 Remission861 (12.27)97 (1.38)26 (0.37)0 (0)
 Low95 (1.35)513 (7.31)140 (2.0)6 (0.09)
 Moderate52 (0.74)215 (3.06)1501 (21.39)271 (3.86)
 High1 (0.01)8 (0.11)279 (3.98)2958 (42.16)83.13%0.75
  • * Values represent number of patients (per cent of all patients).

  • p Value <0.001

  • CDAI, Clinical Disease Activity Index; DAS28, Disease Activity Score based on 28 joint evaluation; GH, patient's assessment of general health; PTGL, patient's global assessment of disease activity; RAPID3, Routine Assessment of Patient Index Data 3.