Characteristics of disease activity, physical function and quality of life
| Characteristics | Patients with axSpA (n=100) | nraxSpA (n=44) | AS (n=56) | p Value |
|---|---|---|---|---|
| Global pain* | 4.4±2.5 | 4.0±2.1 | 4.7±2.7 | 0.2 |
| BASDAI, total | 3.9±2.0 | 3.6±1.7 | 4.2±2.2 | 0.2 |
| BASDAI <4 (n=51) | 2.4±1.0 | 2.4±0.9 | 2.3±1.0 | 0.5 |
| BASDAI ≥4 (n=49) | 5.6±1.3 | 5.1±1.0 | 5.9±1.4 | 0.05 |
| ASDAS total | 2.6±0.9 | 2.2±0.8 | 2.9±0.9 | 0.001 |
| ASDAS <2.1 (n=32) | 1.5±0.4 | 1.5±0.4 | 1.5±0.4 | 0.9 |
| ASDAS ≥2.1 (n=68) | 3.1±0.6 | 2.9±0.5 | 3.2±0.7 | 0.03 |
| Patient's global assessment† | 4.3±2.7 | 4.0±2.7 | 4.6±2.7 | 0.3 |
| Physician's global assessment† | 3.2±1.9 | 2.7±1.7 | 3.5±1.9 | 0.06 |
| BASFI | 2.9±2.3 | 2.4±2.1 | 3.2±2.4 | 0.05 |
| SF-36 mental component summary score | 46.4±11.9 | 45.0±12.3 | 47.5±11.5 | 0.4 |
| SF-36 physical component summary score | 37.6±9.8 | 39.0±9.0 | 36.5±10.2 | 0.2 |
| ASQoL | 5.8±4.8 | 5.6±4.8 | 6.0±4.8 | 0.7 |
| CRP, mean±SD mg/l | 9.0±10.7 | 5.7±6.5 | 11.6±12.6 | <0.001 |
| CRP, BASDAI <4 | 8.9±9.9 | 5.9±6.5 | 11.7±11.7 | 0.04 |
| CRP, BASDAI ≥4 | 9.1±11.7 | 5.4±6.8 | 11.6±13.6 | 0.005 |
| CRP, ASDAS, <2.1 | 3.4±3.5 | 2.3±2.2 | 5.2±4.5 | 0.04 |
| CRP, ASDAS, ≥2.1 | 11.7±12.0 | 8.6±7.6 | 13.4±13.6 | 0.07 |
↵* Numerical rating scales (NRS) for global pain on a 0–10 NRS.
↵† Visual analogue scale for physician and patient's global assessment of disease activity: 0–10 cm.
SF-36 norms for the German population are available.11
ASDAS, Ankylosing Spondylitis Disease Activity Score; ASQoL, Ankylosing Spondylitis Quality of Life; BASDAI, Bath Ankylosing Spondylitis Disease Activity Index; BASFI, Bath AS Functional Index; CRP, C-reactive protein; nraxSpA, non-radiographic axial spondyloarthritis; SF-36, Short Form-36 Health Survey.