Table 5

Associations between sum scores of MRI features and total scores of AUSCAN pain subscale, AUSCAN physical function subscale, FIHOA, AIMS-2 hand/finger subscale and grip strength (adjusted for age and sex)

AUSCAN pain B (95% CI)AUSCAN physical B (95% CI)AIMS-2 B (95% CI)FIHOA B (95% CI)Grip strength B (95% CI)
Osteophytes0.08 (−0.02 to 0.19)0.10 (−0.10 to 0.30)0.08 (−0.05 to 0.20)0.23 (0.07 to 0.39)*−0.39 (−0.58 to −0.21)*
Joint space narrowing0.01 (−0.16 to 0.18)0.04 (−0.28 to 0.36)0.03 (−0.16 to 0.23)0.28 (0.01 to 0.54)*−0.53 (−0.84 to −0.23)*
Erosions0.05 (−0.09 to 0.20)0.06 (−0.22 to 0.34)−0.007 (−0.18 to 0.16)0.20 (−0.02 to 0.43)−0.43 (−0.69 to −0.16)*
Bone attrition0.23 (−0.03 to 0.49)0.34 (−0.16 to 0.83)0.07 (−0.24 to 0.38)0.58 (0.18 to 0.97)*−0.87 (−1.34 to −0.39)*
Cysts0.02 (−0.99 to 1.03)0.08 (−1.84 to 2.01)0.02 (−1.16 to 1.21)0.64 (−0.95 to 2.24)−0.03 (−1.99 to 1.93)
Malalignment0.66 (−0.57 to 1.90)1.66 (−0.47 to 3.78)1.18 (−0.13 to 2.48)1.76 (−0.10 to 3.62)−1.57 (−3.73 to 0.60)
Synovitis0.02 (−0.26 to 0.30)0.19 (−0.33 to 0.71)0.11 (−0.23 to 0.44)0.45 (0.01 to 0.89)*−0.48 (−1.02 to 0.05)
Flexor tenosynovitis−0.33 (−0.65 to −0.001)*−0.31 (−0.94 to 0.32)−0.33 (−0.74 to 0.07)−0.09 (−0.63 to 0.45)−0.14 (−0.80 to 0.53)
BMLs−0.03 (−0.33 to 0.28)−0.01 (−0.59 to 0.57)0.16 (−0.20 to 0.52)0.14 (−0.34 to 0.63)−0.25 (−0.84 to 0.34)
CL absence0.08 (−0.11 to 0.26)0.12 (−0.24 to 0.49)0.12 (−0.10 to 0.34)0.25 (−0.05 to 0.55)−0.22 (−0.58 to 0.15)
BMLs at CL insertions−0.02 (−0.45 to 0.41)−0.04 (−0.86 to 0.78)0.26 (−0.24 to 0.76)0.15 (−0.54 to 0.83)−0.20 (−1.03 to 0.63)
  • Data presented as unstandardised B coefficients (95% CI) from corrected univariate analyses (separate linear regression models adjusted for age and sex).

  • * p<0.05.

  • AIMS-2, Arthritis Impact Measurement Scale 2; AUSCAN, Australian/Canadian hand index; BMLs, bone marrow lesions; CL, collateral ligament; FIHOA, Functional Index of hand osteoarthritis.