Associations between sum scores of MRI features and total scores of AUSCAN pain subscale, AUSCAN physical function subscale, FIHOA, AIMS-2 hand/finger subscale and grip strength (adjusted for age and sex)
| AUSCAN pain B (95% CI) | AUSCAN physical B (95% CI) | AIMS-2 B (95% CI) | FIHOA B (95% CI) | Grip strength B (95% CI) | |
|---|---|---|---|---|---|
| Osteophytes | 0.08 (−0.02 to 0.19) | 0.10 (−0.10 to 0.30) | 0.08 (−0.05 to 0.20) | 0.23 (0.07 to 0.39)* | −0.39 (−0.58 to −0.21)* |
| Joint space narrowing | 0.01 (−0.16 to 0.18) | 0.04 (−0.28 to 0.36) | 0.03 (−0.16 to 0.23) | 0.28 (0.01 to 0.54)* | −0.53 (−0.84 to −0.23)* |
| Erosions | 0.05 (−0.09 to 0.20) | 0.06 (−0.22 to 0.34) | −0.007 (−0.18 to 0.16) | 0.20 (−0.02 to 0.43) | −0.43 (−0.69 to −0.16)* |
| Bone attrition | 0.23 (−0.03 to 0.49) | 0.34 (−0.16 to 0.83) | 0.07 (−0.24 to 0.38) | 0.58 (0.18 to 0.97)* | −0.87 (−1.34 to −0.39)* |
| Cysts | 0.02 (−0.99 to 1.03) | 0.08 (−1.84 to 2.01) | 0.02 (−1.16 to 1.21) | 0.64 (−0.95 to 2.24) | −0.03 (−1.99 to 1.93) |
| Malalignment | 0.66 (−0.57 to 1.90) | 1.66 (−0.47 to 3.78) | 1.18 (−0.13 to 2.48) | 1.76 (−0.10 to 3.62) | −1.57 (−3.73 to 0.60) |
| Synovitis | 0.02 (−0.26 to 0.30) | 0.19 (−0.33 to 0.71) | 0.11 (−0.23 to 0.44) | 0.45 (0.01 to 0.89)* | −0.48 (−1.02 to 0.05) |
| Flexor tenosynovitis | −0.33 (−0.65 to −0.001)* | −0.31 (−0.94 to 0.32) | −0.33 (−0.74 to 0.07) | −0.09 (−0.63 to 0.45) | −0.14 (−0.80 to 0.53) |
| BMLs | −0.03 (−0.33 to 0.28) | −0.01 (−0.59 to 0.57) | 0.16 (−0.20 to 0.52) | 0.14 (−0.34 to 0.63) | −0.25 (−0.84 to 0.34) |
| CL absence | 0.08 (−0.11 to 0.26) | 0.12 (−0.24 to 0.49) | 0.12 (−0.10 to 0.34) | 0.25 (−0.05 to 0.55) | −0.22 (−0.58 to 0.15) |
| BMLs at CL insertions | −0.02 (−0.45 to 0.41) | −0.04 (−0.86 to 0.78) | 0.26 (−0.24 to 0.76) | 0.15 (−0.54 to 0.83) | −0.20 (−1.03 to 0.63) |
Data presented as unstandardised B coefficients (95% CI) from corrected univariate analyses (separate linear regression models adjusted for age and sex).
↵* p<0.05.
AIMS-2, Arthritis Impact Measurement Scale 2; AUSCAN, Australian/Canadian hand index; BMLs, bone marrow lesions; CL, collateral ligament; FIHOA, Functional Index of hand osteoarthritis.