Tight control (n=126) | Usual care (n=126) | p Value* | |
---|---|---|---|
DAS28 (mean (±SD)) | −2.5 (1.3) | −1.5 (1.4) | 0.000 |
HAQ score (median (IQR) | −0.5 (−1–−0.2) | −0.3 (−0.8–0) | 0.003 |
Swollen joint count (median (IQR)) | −7 (−10−3) | −3 (−8–0) | 0.000 |
Tender joint count (median (IQR)) | −4 (−8–−1) | −2 (−6–0) | 0.000 |
ESR (median (IQR)) | −11 (−28–−2) | −12 (−25–−1) | 0.542 |
CRP (median (IQR)) | −5 (−28–0) | −3 (−21–0) | 0.397 |
VAS pain (mean (SD)) | −30 (27) | −16 (28) | 0.000 |
VAS GH (mean (SD)) | −32 (28) | −16 (27) | 0.000 |
The negative values indicate improvement from baseline.
IQR, P25–P75.
↵* p value for between group comparisons.
CRP, C reactive protein; DAS28, Disease Activity Score based on 28 joint counts; ESR, erythrocyte sedimentation rate; GH, general health; HAQ, Health Assessment Questionnaire; VAS, Visual Analogue Scale.