Table 1

Association statistics for susceptibility to psoriatic arthritis for the 44 successfully genotype SNPs

NumberMAFGenotype countsGenotype frequenciesHWEp Value95% CI
MarkerChrGeneCaseControlsCasesControlsCasesControlsCasesControlsCasesControlsTrendORLowerUpper
rs24766011PTPN2298255680.110.1015/185/78245/991/45321.5/18.8/79.60.8/17.8/81.40.3230.2840.088631.140.981.34
rs115862381CD298057500.240.2365/342/573330/2036/33846.6/34.9/58.55.7/35.4/58.90.1620.3040.54191.040.931.16
rs75431741IL6R97255600.170.1825/277/670174/1656/37302.6/28.5/68.93.1/29.8/67.10.6470.5860.20.920.811.05
rs130312372REL97255600.340.38115/431/426781/2617/216211.8/44.3/43.814.0/47.1/38.90.7210.8190.0025690.860.770.95
rs130175992REL97155530.330.38107/436/428781/2612/216011.0/44.9/44.114.1/47.0/38.90.8290.8640.00052420.840.750.93
rs11605422AFF398155680.470.46229/472/2801157/2798/161323.3/48.1/28.520.8/50.3/29.00.2770.3880.21941.060.961.17
rs108650352AFF398132960.480.46237/472/272667/1678/95124.2/48.1/27.720.2/50.9/28.90.2500.1500.047751.111.001.22
rs101816562STAT498038320.250.2267/359/554180/1327/23256.8/36.6/56.54.7/34.6/60.70.3970.6380.0030321.191.061.34
rs19804222CD2897557470.250.2354/372/549273/2051/34235.5/38.2/56.34.8/35.7/59.60.4370.1310.04711.121.001.25
rs2317752CTLA497155680.390.39144/468/359852/2675/204114.8/48.2/37.015.3/48.0/36.70.6860.6330.74190.980.891.09
rs30872432CTLA497857480.430.44162/511/3051126/2850/177216.6/52.2/31.219.6/49.6/30.80.0370.7490.16090.930.851.03
rs45352113PLCL297557450.530.49262/503/2101376/2857/151226.9/51.6/21.524.0/49.7/26.30.3040.7120.0016631.171.061.28
rs133155913FAM107A97357400.090.086/164/80337/878/48250.6/16.9/82.50.6/15.3/84.10.5600.7290.26711.100.931.30
rs8740404RBPJ97257040.320.30100/423/449511/2404/278910.3/43.5/46.29.0/42.1/48.91.0000.8500.07361.100.991.22
rs20697784IL296036990.160.1819/269/672124/1086/24892.0/28.0/70.03.4/29.4/67.30.2290.6970.036110.870.760.99
rs68228444IL2195855490.160.1720/264/674155/1631/37632.1/27.6/70.42.8/29.4/67.80.3960.1780.079370.890.781.02
rs100403275ANKRD5597057370.100.127/186/777102/1139/44960.7/19.2/80.11.8/19.9/78.40.3000.0040.079120.870.741.01
rs262325C5orf3097255580.320.3395/430/447575/2511/24729.8/44.2/46.010.3/45.2/44.50.6060.0950.36140.950.861.06
rs5482346PRDM198057510.310.3392/423/465604/2599/25489.4/43.2/47.410.5/45.2/44.30.8230.1290.060980.910.821.01
rs132070336TNFAIP396057230.260.2863/371/526451/2260/30126.6/38.6/54.87.9/39.5/52.60.8670.3550.11540.920.821.02
rs69202206TNFAIP395957230.210.2248/312/599289/1968/34665.0/32.5/62.55.0/34.4/60.60.3850.6470.34490.940.841.06
rs50299376TNFAIP395634470.030.032/52/9025/229/32130.2/5.4/94.40.1/6.6/93.20.1910.6070.25080.840.631.13
rs3945816TAGAP97829880.320.31102/417/459298/1271/141910.4/42.6/46.910.0/42.5/47.50.6060.5800.67671.020.921.14
rs30930236CCR696857350.420.43146/523/2991099/2778/185815.1/54.0/30.919.2/48.4/32.40.0010.2950.290.950.861.05
rs420417CDK698257470.260.2562/387/533342/2144/32616.3/39.4/54.36.0/37.3/56.70.5070.6960.17811.080.971.20
rs104886317IRF597355590.110.1114/194/76559/1085/44151.4/19.9/78.61.1/19.5/79.40.6350.4440.44121.060.911.24
rs27363408BLK97157410.240.2550/373/548330/2158/32535.1/38.4/56.45.7/37.6/56.70.2220.2690.85850.990.891.11
rs28123789CCL2196057230.370.34138/433/389643/2615/246514.4/45.1/40.511.2/45.7/43.10.3320.2060.014751.131.021.25
rs9510059CCL2197355580.160.1527/249/697111/1406/40412.8/25.6/71.62.0/25.3/72.70.3940.4210.28761.080.941.23
rs107601309TRAF1/C595955490.440.44189/466/3041089/2680/178019.7/48.6/31.719.6/48.3/32.10.6940.1640.85231.010.921.11
rs29001809TRAF1/C598255700.350.35120/445/417706/2479/238512.2/45.3/42.512.7/44.5/42.80.9440.1180.96591.000.901.10
rs70677810IL2RA96557400.420.40193/432/340936/2737/206720.0/44.8/35.216.3/47.7/36.00.0100.5640.066691.100.991.21
rs210428610IL2RA98057430.270.2873/390/517462/2297/29847.4/39.8/52.88.0/40.0/52.01.0000.4930.52720.970.871.08
rs1159465610IL2RA97657490.230.2466/320/590342/2087/33206.8/32.8/60.55.9/36.3/57.70.0150.5640.37050.950.851.06
rs475031610PRKCQ98257490.170.1924/290/668222/1745/37822.4/29.5/68.03.9/30.4/65.80.3130.2480.05620.880.781.00
rs54038611TRAF697357360.140.1324/215/734101/1327/43082.5/22.1/75.41.8/23.1/75.10.0980.9550.82341.020.881.17
rs167854212KIF5A95857230.420.39184/434/340896/2675/215219.2/45.3/35.515.7/46.7/37.60.0340.1820.020481.131.021.24
rs318450412SH2B396355550.500.49248/467/2481298/2819/143825.8/48.5/25.823.4/50.7/25.90.3670.2480.3051.050.951.16
rs723402918PTNP297257310.170.1624/273/675128/1536/40672.5/28.1/69.42.2/26.8/71.00.6420.2490.32191.070.941.22
rs481048520CD4096057230.250.2466/354/540332/2088/33036.9/36.9/56.25.8/36.5/57.70.4430.9420.23081.070.961.20
rs1120320321UBASH3A96657310.350.37119/440/407786/2696/224912.3/45.5/42.113.7/47.0/39.21.0000.6510.070260.910.821.01
rs321825822IL2RB97955690.270.2676/379/524381/2161/30277.8/38.7/53.56.8/38.8/54.40.5180.8900.41751.050.941.17
rs74377722IL2RB96057230.330.31100/431/429549/2450/272410.4/44.9/44.79.6/42.8/47.60.6090.9750.1021.090.981.21
  • Chr, chromosome; HWE, Hy–Weinberg equilibrium; MAF, minor allele frequency; SNP, single nucleotide polymorphism.