Age and multivariate-adjusted RRs for the association of adiposity measurements with risk of psoriatic arthritis among participants with confirmed psoriasis
| Cases | Person-years | Age-adjusted RR (95% CI) | Multivariate-adjusted RR* (95% CI) | |
|---|---|---|---|---|
| Updated BMI (kg/m2) | 146 | 6838 | ||
| <25.0 | 40 | 3245 | 1.00 | 1.00 |
| 25.0–29.9 | 35 | 1533 | 1.80 (1.12 to 2.88) | 1.81 (1.12 to 2.93) |
| 30.0–34.9 | 28 | 1051 | 1.98 (1.19 to 3.28) | 1.90 (1.13 to 3.18) |
| ≥35.0 | 43 | 1009 | 2.97 (1.88 to 4.69) | 2.98 (1.86 to 4.78) |
| p for trend | <0.0001 | |||
| BMI at age 18 years (kg/m2) | 145 | 6791 | ||
| <21.0 | 67 | 3265 | 1.23 (0.77 to 1.96) | 1.28 (0.79 to 2.06) |
| 21.0–22.9 | 26 | 1668 | 1.00 | 1.00 |
| 23.0–24.9 | 24 | 858 | 1.74 (0.98 to 3.09) | 1.73 (0.96 to 3.13) |
| 25.0–29.9 | 17 | 610 | 1.69 (0.89 to 3.20) | 1.69 (0.88 to 3.26) |
| ≥30.0 | 11 | 390 | 1.61 (0.76 to 3.42) | 1.53 (0.71 to 3.29) |
| p for trend | 0.10 | 0.20 | ||
| Weight change from age 18 years (lb) | 145 | 6791 | ||
| Loss or increase of <20.0 | 32 | 2669 | 1.00 | 1.00 |
| Increase of 20.0–49.9 | 45 | 2285 | 1.36 (0.84 to 2.18) | 1.34 (0.82 to 2.17) |
| Increase of 50.0–99.9 | 50 | 1513 | 2.31 (1.46 to 3.68) | 2.42 (1.49 to 3.91) |
| Increase of ≥100.0 | 18 | 324 | 3.28 (1.76 to 6.11) | 3.84 (1.93 to 7.63) |
| p for trend | <0.0001 | <0.0001 | ||
| Waist circumference (inches) | 72 | 3272 | ||
| Tertile 1, <28.0 | 7 | 746 | 1.00 | 1.00 |
| Tertile 2, 28.0–31.9 | 17 | 1045 | 1.67 (0.63 to 4.38) | 1.46 (0.54 to 3.99) |
| Tertile 3, ≥32.0 | 48 | 1481 | 3.23 (1.36 to 7.69) | 3.02 (1.21 to 7.56) |
| p for trend | 0.002 | 0.004 | ||
| Hip circumference (inches) | 70 | 3245 | ||
| Tertile 1, <38.0 | 13 | 931 | 1.00 | 1.00 |
| Tertile 2, 38.0–40.9 | 13 | 917 | 1.31 (0.56 to 3.05) | 1.24 (0.51 to 3.00) |
| Tertile 3, ≥41.0 | 44 | 1397 | 2.35 (1.15 to 4.79) | 2.59 (1.18 to 5.69) |
| p for trend | 0.009 | 0.006 | ||
| Waist–hip ratio | 70 | 3245 | ||
| Tertile 1, <0.744 | 12 | 1008 | 1.00 | 1.00 |
| Tertile 2, 0.744–0.800 | 20 | 996 | 1.43 (0.67 to 3.06) | 1.41 (0.63 to 3.15) |
| Tertile 3, >0.800 | 38 | 1241 | 2.36 (1.18 to 4.74) | 2.48 (1.20 to 5.15) |
| p for trend | 0.009 | 0.008 |
↵* Adjusted for age (continuous variable), smoking (never, past, current with 1–14, 15–24, or ≥25 cigarettes/day), alcohol drinking (no, <4.9, 5.0–9.9, 10–14.9, 15–29.9 or ≥30.0 g/day), vigorous physical activity (metabolic equivalent hours/week, in quintile), and height (inches, for the analysis of waist circumference, hip circumference and waist–hip ratio) and weight at 18 years (for the analysis of weight change from 18 years).
BMI, body mass index.