Table 2

OR for seroprotection in JIA patients in comparison with healthy controls

Percentage with protective antibody concentrations
SeroprotectionNJIAHCUnadjusted OR (95% CI)p ValueAdjusted OR* (95% CI)p Value
Cohort ≥1986
 Measles178093.987.42.2 (1.4 to 3.5)0.0011.4 (0.8 to 2.5)0.233
 Mumps178385.185.01.0 (0.7 to 1.4)0.9530.4 (0.3 to 0.6)<0.001
 Rubella178289.890.30.9 (0.6 to 1.4)0.7890.4 (0.3 to 0.7)0.001
 Diphtheria162190.598.50.1 (0.08 to 0.3)<0.0010.1 (0.06 to 0.2)<0.001
 Tetanus162195.799.10.2 (0.1 to 0.5)<0.0010.1 (0.05 to 0.3)<0.001
Cohort 1976–85
 Measles79194.691.01.7 (0.4 to 7.4)0.4552.1 (0.5 to 9.2)0.319
 Mumps79081.194.80.2 (0.1 to 0.6)0.0010.1 (0.05 to 0.4)<0.001
 Rubella79181.198.80.05 (0.02 to 0.1)<0.0010.03 (0.01 to 0.1)<0.001
 Diphtheria78377.198.90.04 (0.01 to 0.1)<0.0010.04 (0.01 to 0.1)<0.001
 Tetanus78394.399.30.1 (0.02 to 0.6)0.0100.1 (0.02 to 0.6)0.010
  • * The OR indicates the odds of having protective antibody levels for JIA patients compared with healthy controls. In logistic regression analysis the OR were adjusted for age and the number of vaccinations at the time of sampling.

  • HC, healthy controls; JIA, juvenile idiopathic arthritis.