Table 1

Clinical and laboratory profile of adult patients with DM or PM positive for anti-NXP2 Ab

PatientABCDEFGH
Age (years)2334545757616268
SexMaleFemaleMaleMaleMaleMaleMemaleMale
DiagnosisDMDMDMDMDMDMPMDM
Duration (months)112110823427
Heliotrope rash+++++
Gottron's sign++++
Perionychia erythema++++
Nailfold punctuated haemorrhage++++
V sign+++
Shawl sign+++
Scratch dermatitis+++
Erythema of extensor extremities+++++
Calcinosis
Blistering
Ulceration+
Muscle weakness++++++++
Raynaud's phenomenon
Fever+++++
Arthralgia+
Elevation of CK++++++++
Highest CK level (IU/l)3857187749271539171402668537133722
IIF titre<4080<4040<40<4080<40
IIF staining patternSpSpSp
ILD
Malignancy++++
 OriginProstatePancreasGallbladderLung
 HistologyACNDACSCC
 StageIVIVbIVbIIIb
 Period of diagnosis*42 months before6 months afterSimultaneous3 months before
  • * Period of diagnosis indicates when the diagnosis of malignancy was made before or after the onset of idiopathic inflammatory myopathies.

  • AC, adenocarcinoma; CK, creatine kinase; DM, dermatomyositis; IIF, indirect immunofluorescence; ILD, interstitial lung disease; ND, not done; PM, polymyositis; Sp, speckled; SSC, squamous cell carcinoma.