Table 1

Baseline demographics and disease characteristics

VariableAny ADA exposure (N=311)
Sex, n (%) male233 (74.9)
Race, n (%) white299 (96.1)
Age, mean (SD) years42.3 (11.6)
HLA-B27+, n (%)245 (78.8)
Disease duration, mean (SD) years11.00 (9.5)
Abnormal CRP, n (%) ≥0.49 mg/dl211 (67.8)
BASDAI, mean (SD) cm (0–10 VAS)6.3 (1.7)
Patient global assessment, mean (SD) mm (0–100 VAS)*63.6 (20.9)
Physician global assessment, mean (SD) mm (0–100 VAS)*57.3 (18.6)
Total back pain, mean (SD) mm (0–100 VAS)65.3 (21.1)
BASFI, mean (SD) mm (0–100 VAS)53.8 (22.1)
Inflammation, mean (SD) cm (0–10 VAS)6.7 (2.0)
≥1 syndesmophyte, n (%)188 (85.8)
  • * N=310.

  • Mean of BASDAI question 5 and 6.

  • N=219.

  • ADA, adalimumab; BASDAI, Bath Ankylosing Spondylitis Disease Activity Index; BASFI, Bath Ankylosing Spondylitis Functional Index; CRP, C-reactive protein; HLA, human leucocyte antigen; VAS, visual analogue scale.