Table 2

Estimated accuracy and diagnostic certainty in detecting ILD on secondary reconstructed HRCT image series

Image Series
S1S2S3
Sensitivity (95% CI)100%94% (76.7% to 99.6%)92% (74.0% to 99.0%)
Specificity (95% CI)95% (75.1 to 99.9%)95% (75.1 to 99.9%)97.5 (78.9% to 100%)
Accuracy97.8%94.4%94.4%
High diagnostic certainty*93%90%92%
  • Values are average between the two readers.

  • * degree of confidence score 1 or 4 (ie, 1, certain that ILD present; 2, certain no ILD present).

  • HRCT, high-resolution CT; ILD, interstitial lung disease; S1, series 1 (10 mm increment); S2, series 2 (seven images with baso-apical gradient); S3, series 3 (three images obtained apical, in the middle and basal zone, respectively).