Association between statin use and progression of knee and hip osteoarthritis
| Knee osteoarthritis | Hip osteoarthritis | |||||||
|---|---|---|---|---|---|---|---|---|
| Progressors, N (%) | Adjusted OR | 95% CI | p Value | Progressors, N (%) | Adjusted OR | 95% CI | p Value | |
| Non-users | 288 (7.3) | 1.00 | – | – | 177 (4.5) | 1.00 | – | – |
| Statin users | 15 (3.0) | 0.43 | 0.25 to 0.77 | 0.01 | 21 (4.0) | 1.10 | 0.63 to 1.90 | 0.74 |
| Period of statin use (days) | ||||||||
| Non-users | 346 (7.2) | 1.00 | – | – | 228 (4.8) | 1.00 | – | – |
| 1–119 | 53 (6.3) | 1.77 | 0.71 to 4.44 | 0.22 | 3 (4.1) | 1.05 | 0.20 to 5.62 | 0.95 |
| 120–364 | 3 (2.4) | 0.30 | 0.08 to 1.19 | 0.09 | 6 (4.8) | 1.05 | 0.38 to 2.88 | 0.92 |
| ≥365 | 18 (4.1) | 0.49 | 0.26 to 0.92 | 0.03 | 17 (3.6) | 1.00 | 0.51 to 1.98 | 0.92 |