Table 2

Comparison of clinical and laboratory profile of adult patients with dermatomyositis with anti-NXP2 Ab, anti-TIF1 Ab and anti-Mi-2 Ab*

p Values
Anti-NXP2-positiveAnti-TIF1-positiveAnti-Mi-2-positivevs Anti-TIF1vs Anti-Mi-2
Number77415
Age at onset, mean (range)57 (23–68)59 (27–89)50 (16–67)NSNS
Sex (male:female)6:124:348:70.033NS
Skin eruptions
 Heliotrope rash716260NSNS
 Gottron's sign578187NSNS
 Perionychia erythema575760NSNS
 Nailfold punctuated haemorrhage574073NSNS
 Trunk erythema576253NSNS
 Calcinosis027NSNS
 Ulceration1470NSNS
Clinical features
 Muscle weakness1006993NSNS
 Raynaud's phenomenon090NSNS
 Arthritis1437NSNS
 Fever5716200.025NS
Organ involvement
 Interstitial lung disease01313NSNS
 Internal malignancy within 3 years29667NSNS
Laboratory findings
 Elevated CK, %10063100NSNS
 Highest CK level, IU/l, mean (range)3857 (1539–26685)425 (40–8670)3934 (401–10000)<0.001NS
  • * Unless noted otherwise, values are percentages.

  • CK, creatine kinase.