Male | Female | ||||||||
---|---|---|---|---|---|---|---|---|---|
Risk allele frequency | Risk allele frequency | ||||||||
SNP | Gene locus | Case | Control | OR (95% CI) | p Value | Case | Control | OR (95% CI) | p Value |
rs2476601 | PTPN22 | 0.102 | 0.081 | 1.28 (0.96 to 1.71) | 0.089 | 0.110 | 0.0802 | 1.41(1.24 to 1.61) | 1.5×10−7 |
rs1801274 | FCGR2A | 0.528 | 0.499 | 1.13 (0.94 to 1.34) | 0.18 | 0.542 | 0.513 | 1.13 (1.05 to 1.21) | 0.0017 |
rs2205960 | TNFSF4 | 0.276 | 0.209 | 1.44 (1.19 to 1.75) | 2.3×10−4 | 0.269 | 0.2167 | 1.33 (1.22 to 1.45) | 1.6×10−10 |
rs7574865 | STAT4 | 0.285 | 0.213 | 1.47 (1.21 to 1.79) | 1.2×10−4 | 0.309 | 0.2302 | 1.49 (1.37 to 1.63) | 4.0×10−20 |
rs231775 | CTLA4 | 0.352 | 0.346 | 1.03 (0.86 to 1.23) | 0.79 | 0.362 | 0.3475 | 1.07 (0.87 to 1.01) | 0.11 |
rs11568821 | PDCD1 | 0.878 | 0.875 | 1.03 (0.79 to 1.34) | 0.83 | 0.889 | 0.8851 | 1.04 (0.93 to 1.18) | 0.47 |
rs6445975 | PXK | 0.311 | 0.280 | 1.16 (0.96 to 1.40) | 0.12 | 0.291 | 0.2564 | 1.19 (1.10 to 1.30) | 3.6×10−5 |
rs10516487 | BANK1 | 0.746 | 0.675 | 1.42 (1.17 to 1.72) | 4.3×10−4 | 0.737 | 0.701 | 1.19 (1.10 to 1.30) | 2.8×10−5 |
rs907715 | IL21 | 0.680 | 0.655 | 1.12 (0.93 to 1.34) | 0.23 | 0.687 | 0.656 | 1.15 (1.06 to 1.24) | 5.2×10−4 |
rs3131379 | HLA Region 1 | 0.222 | 0.099 | 2.61 (2.08 to 3.27) | 1.3×10−17 | 0.172 | 0.0923 | 2.05 (1.82 to 2.30) | 1.7×10−34 |
rs1270942 | HLA Region 2 | 0.225 | 0.097 | 2.71 (2.16 to 3.40) | 5.9×10−19 | 0.172 | 0.0921 | 2.05 (1.82 to 2.30) | 2.1×10−34 |
rs729302 | IRF5 | 0.737 | 0.684 | 1.23 (1.02 to 1.49) | 0.032 | 0.745 | 0.675 | 1.41 (1.30 to 1.53) | 1.3×10−16 |
rs2070197 | IRF5 | 0.204 | 0.106 | 2.15 (1.71 to 2.69) | 2.6×10−11 | 0.172 | 0.1028 | 1.82 (1.62 to 2.03) | 9.3×10−26 |
rs10954213 | IRF5 | 0.699 | 0.639 | 1.31 (1.09 to 1.58) | 0.0038 | 0.678 | 0.618 | 1.30 (1.21 to 1.41) | 1.9×10−11 |
rs13277113 | C8orf13-BLK | 0.321 | 0.229 | 1.60 (1.32 to 1.93) | 1.3×10−6 | 0.288 | 0.2421 | 1.27 (1.16 to 1.38) | 6.5×10−8 |
rs1800450 | MBL | 0.143 | 0.140 | 1.03 (0.80 to 1.31) | 0.83 | 0.146 | 0.1392 | 1.05 (0.85 to 1.06) | 0.34 |
rs4963128 | KIAA1542 | 0.664 | 0.673 | 0.96 (0.80 to 1.15) | 0.68 | 0.712 | 0.664 | 1.25 (1.15 to 1.35) | 4.7×10−8 |
rs1143679 | ITGAM | 0.201 | 0.138 | 1.57 (1.26 to 1.96) | 5.4×10−5 | 0.193 | 0.1202 | 1.75 (1.58 to 1.95) | 1.3×10−25 |
SNP, single nucleotide polymorphism.