The association between smoking status and PsA* (N=654) compared with psoriasis alone (N=401) by logistic regression analysis, adjusted for age, sex, level of education, alcohol consumption, duration and severity of psoriasis
Univariate model | Multivariate model | |||||
---|---|---|---|---|---|---|
Covariate | OR | 95% CI | p Value | OR | 95% CI | p Value |
Smoking status | ||||||
Current vs life-time non- smokers | 0.66 | 0.48 to 0.90 | 0.009 | 0.57 | 0.41 to 0.81 | 0.002 |
Past vs life-time non- smokers | 0.63 | 0.46 to 0.84 | 0.002 | 0.81 | 0.56 to 1.12 | 0.21 |
Age group, years† | ||||||
31–40 | 0.42 | 0.28 to 0.62 | <0.0001 | 0.49 | 0.33 to 0.75 | 0.0009 |
41–50 | 0.34 | 0.23 to 0.51 | <0.0001 | 0.43 | 0.28 to 0.65 | <0.0001 |
51–60 | 0.14 | 0.09 to 0.22 | <0.0001 | 0.18 | 0.11 to 0.28 | <0.0001 |
>60 | 0.10 | 0.06 to 0.17 | <0.0001 | 0.06 | 0.07 to 0.23 | <0.0001 |
Sex: male vs female | 0.91 | 0.71 to 1.17 | 0.47 | 1.03 | 0.78 to 1.36 | 0.85 |
Duration of psoriasis, years‡ | ||||||
6–10 | 0.85 | 0.58 to 1.25 | 0.41 | 0.70 | 0.47 to 1.06 | 0.09 |
11–15 | 0.66 | 0.43 to 1.02 | 0.06 | 0.49 | 0.31 to 0.79 | 0.003 |
16–20 | 0.45 | 0.28 to 0.70 | 0.0005 | 0.46 | 0.28 to 0.74 | 0.002 |
21 and more | 0.26 | 0.19 to 0.37 | <0.0001 | 0.37 | 0.26 to 0.53 | <0.0001 |
Alcohol consumption | ||||||
Social vs none | 0.92 | 0.69 to 1.22 | 0.55 | 0.94 | 0.68 to 1.28 | 0.67 |
Daily vs none | 1.17 | 0.74 to 1.84 | 0.50 | 1.65 | 0.99 to 2.76 | 0.05 |
Severe psoriasis: yes vs no | 2.13 | 1.56 to 2.91 | <0.0001 | 2.07 | 1.47 to 2.92 | <0.0001 |
↵* Psoriatic arthritis (PsA) is the outcome variable.
↵† Age at the time of the diagnosis for PsA and at first study visit for psoriasis. The reference group is 30 years and younger.
↵‡ Duration of psoriasis at the time of the diagnosis of PsA (for PsA) and at first study visit (for psoriasis). The reference group is 5 years and less