KLG 0 | KLG 1 | KLG 2 | KLG 3–4 | |
---|---|---|---|---|
Osteophytes* | 1.0 | 3.8 (2.1 to 7.0); p<0.001 | 14 (7.5 to 26); p<0.001 | 415 (189 to 908); p<0.001 |
Joint space narrowing | 1.0 | 1.9 (1.2 to 2.8); p=0.003 | 2.0 (1.3 to 3.3); p=0.003 | 9.6 (4.3 to 22); p<0.001 |
Erosions | 1.0 | 2.8 (1.9 to 4.1); p<0.001 | 5.0 (3.4 to 7.2); p<0.001 | 25 (16 to 40); p<0.001 |
Bone attrition | 1.0 | 0.9 (0.4 to 1.8); p=0.75 | 6.0 (3.0 to 12); p<0.001 | 87 (37 to 204); p<0.001 |
Cysts | 1.0 | 0.7 (0.2 to 2.2); p=0.50 | 1.6 (0.5 to 5.2); p=0.43 | 2.0 (0.6 to 6.3); p=0.26 |
Malalignment | 1.0 | 2.1 (0.5 to 8.8); p=0.32 | 4.7 (1.2 to 19); p=0.03 | 27 (8.6 to 87); p<0.001 |
Synovitis | 1.0 | 1.5 (1.0 to 2.1); p=0.03 | 2.1 (1.4 to 3.2); p=0.001 | 1.4 (1.0 to 2.2); p=0.07 |
Flexor tenosynovitis† | 1.0 | 1.4 (0.8 to 2.5); p=0.23 | 1.3 (0.7 to 2.2); p=0.36 | 1.0 (0.5 to 2.0); p=0.99 |
BMLs | 1.0 | 2.6 (1.2 to 5.4); p=0.01 | 4.8 (2.1 to 11); p<0.001 | 11 (5.5 to 21); p<0.001 |
CL absence | 1.0 | 1.8 (1.2 to 2.6); p=0.004 | 2.6 (1.7 to 3.8); p<0.001 | 9.6 (5.7 to 16); p<0.001 |
BMLs at CL insertions | 1.0 | 2.3 (0.8 to 6.3); p=0.12 | 8.2 (2.9 to 23); p<0.001 | 11 (4.1 to 28); p<0.001 |
Joints without osteoarthritis (KL grade 0) serve as reference.
↵* Presence of osteophytes grades 2–3 due to few joints without MRI-defined osteophytes.
↵† Independent correlation matrix (more simple model due to errors in the estimation process).
OR, odds ratio; CI, confidence interval
BMLs, bone marrow lesions; CL, collateral ligament; KL, Kellgren–Lawrence.