Bone mineral density (BMD) and markers of bone physiology and turnover
| Lumbar spine BMD | |
| Median z score (range) | −0.4 (−3.3 to 3.2) |
| Number of patients (−1.0)≤z≤(−2.0) (%) | 17 (21) |
| Number of patients z≤(−2.0) (%) | 8 (10) |
| Hip BMD | |
| Median of mean hip BMD (% (range)) | 99 (64–192) |
| Laboratory assessment of bone health* | |
| Median iPTH (range) (normal 9–55 ng/l) | 31 (3–129) |
| Median corrected calcium (range) (normal 2.19–2.60 mmol/l) | 2.39 (2.01–2.73) |
| Median ionised calcium (range) (normal 1.22–1.37 mmol/l) | 1.21 (0.80–1.32) |
| Median phosphate (range) (normal 0.87–1.52 mmol/l) | 1.33 (0.74–1.89) |
| Median 25 hydroxyvitamin D (range) (normal 70–250 nmol/l) | 40 (10–134) |
| Median alkaline phosphatase (range) (normal 45–140 U/l) | 79 (37–311) |
| Median alkaline phosphatase bone isozyme (range) (normal <73 U/l) | 40 (15–299) |
| Median urine N-telopeptide (nmol BCE/mmol creatinine (range))† | 104 (38–553) |
↵* Data available for different numbers of patients for each parameter: iPTH (44), corrected calcium (79), ionised calcium (46), phosphate (54), 25 hydroxyvitamin D (46), alkaline phosphatase (51), alkaline phosphatase bone isozyme (36), urine N-telopeptide (33).
↵† Only adult ranges are available: men 3–63 nM BCE/mmol creatinine, women 5–65 nM BCE/mmol creatinine.
iPTH, intact parathyroid hormone; BCE, bone collagen equivalent.