Year | Any DMARD | Prednisone | Patients (n) | Methotrexate | Hydroxychloroquine | Leflunomide | Any non-biological DMARD | Etanercept | Infliximab | Adalimumab | Any biological DMARD |
---|---|---|---|---|---|---|---|---|---|---|---|
1983 | 47.0 | 28.8 | 1307 | 2.9 | 9.7 | ||||||
1984 | 50.9 | 29.2 | 1254 | 4.8 | 12.9 | ||||||
1985 | 51.7 | 30.8 | 1248 | 8.9 | 12.3 | ||||||
1986 | 53.1 | 31.1 | 1387 | 12.3 | 11.7 | ||||||
1987 | 54.5 | 33.3 | 1395 | 14.8 | 12.2 | ||||||
1988 | 56.0 | 34.3 | 1504 | 17.4 | 12.2 | ||||||
1989 | 55.3 | 33.5 | 1689 | 19.8 | 11.3 | ||||||
1990 | 55.5 | 34.9 | 1779 | 24.2 | 10.8 | ||||||
1991 | 57.7 | 37.4 | 1693 | 29.7 | 12.5 | ||||||
1992 | 58.6 | 38.7 | 1672 | 33.7 | 13.4 | ||||||
1993 | 61.4 | 40.7 | 1578 | 37.0 | 15.7 | ||||||
1994 | 64.2 | 40.5 | 1687 | 40.5 | 15.9 | ||||||
1995 | 66.2 | 40.6 | 1542 | 43.7 | 17.0 | ||||||
1996 | 66.2 | 41.4 | 1534 | 44.9 | 17.9 | ||||||
1997 | 67.6 | 41.9 | 1864 | 46.9 | 20.2 | ||||||
1998 | 62.9 | 39.9 | 2241 | 44.7 | 22.3 | ||||||
1999 | 64.4 | 40.4 | 1945 | 46.0 | 24.3 | 4.8 | 63.8 | 3.5 | 0.1 | 3.5 | |
2000 | 69.7 | 38.1 | 1571 | 46.2 | 23.4 | 9.2 | 67.2 | 9.9 | 1.6 | 11.4 | |
2001 | 71.1 | 35.3 | 1506 | 46.6 | 23.5 | 10.5 | 66.7 | 13.6 | 4.3 | 17.6 | |
2002 | 71.3 | 33.7 | 1064 | 45.4 | 20.5 | 10.3 | 67.0 | 13.1 | 6.5 | 19.5 | |
2003 | 74.5 | 36.6 | 1201 | 47.4 | 19.6 | 11.8 | 68.6 | 15.8 | 8.0 | 0.8 | 24.2 |
2004 | 75.6 | 36.0 | 1102 | 48.0 | 19.2 | 11.3 | 68.2 | 17.9 | 8.5 | 4.0 | 29.3 |
2005 | 76.0 | 34.3 | 1035 | 48.3 | 17.9 | 10.3 | 67.1 | 19.3 | 8.5 | 5.5 | 32.7 |
2006 | 76.9 | 30.9 | 920 | 48.0 | 19.0 | 9.7 | 66.5 | 21.7 | 8.8 | 7.0 | 36.9 |
Note: Since patients might be on multiple medications, the percentages may add up to greater than 100%.
DMARD, disease-modifying anti-rheumatic drug.