Changes in metacarpal BMD, in absolute value (mg/cm2) and as percentage of baseline BMD, in patients with progressive hand osteoarthritis (OA), non-progressive hand OA and no hand OA over 2 years
| Changes | Progressive hand OA group 1 (n=39) | Non-progressive hand OA group 2 (n=84) | No hand OA group 3 (n=58) |
|---|---|---|---|
| Median (IQR) change in BMD over 2 years, in mg/cm2 | −12.6 (−23.3 to −6.5) | −8.5 (−15.1 to −3.2) | −9.2 (−17.4 to −2.2) |
| p Value, overall | 0.025 | ||
| p Value, group 1 versus 2* | 0.033 | ||
| p Value, group 1 versus 3* | 0.040 | ||
| p Value, group 2 versus 3* | 0.858 | ||
| Median (IQR) change in BMD over 2 years, in % of baseline BMD | −2.2 (−4.1 to −1.4) | −1.4 (−2.9 to −0.6) | −1.4 (−3.1 to −0.4) |
| p Value, overall | 0.032 | ||
| p Value, group 1 versus 2* | 0.045 | ||
| p Value, group 1 versus 3* | 0.042 | ||
| p Value, group 2 versus 3* | 0.604 |
↵* p Values are corrected for multiple testing by the step-down Bonferroni–Holmes adjustment.
BMD, bone mineral density.