Table 2

Performance of three sets of classification criteria for rheumatoid arthritis (RA) or for prediction of erosive disease

Gold standard
Methotrexate within 1 yearExpert opinion RAErosive disease at 3 years
2010 ACR/EULAR1987 ACRVisser algorithm2010 ACR/EULAR1987 ACRVisser algorithm2010 ACR/EULAR1987 ACRVisser algorithm
Sensitivity0.850.760.640.900.810.700.910.970.85
Specificity0.500.590.710.480.590.730.210.170.41
PPV0.860.870.860.790.810.840.220.220.26
NPV0.490.410.370.690.590.540.910.960.92
LR+1.701.852.211.731.982.591.161.171.45
LR−0.300.410.510.210.320.410.420.170.36
AUC (95% CI)0.78 (0.73 to 0.83)0.71 (0.64 to 0.77)0.75 (0.70 to 0.81)0.80 (0.76 to 0.84)0.74 (0.69 to 0.79)0.77 (0.72 to 0.82)0.63 (0.53 to 0.73)0.67 (0.57 to 0.77)0.64 (0.54 to 0.74)
  • ACR, American College of Rheumatology; AUC, area under the curve; EULAR, European League Against Rheumatism; LR, likelihood ratio; NPV, negative predictive value; PPV, positive predictive value.