Predictors of target knee replacement—multivariate analyses
| OR | 95% CI | p Value* | |
|---|---|---|---|
| Baseline predictors only | |||
| Male | 1.189 | 0.341 to 4.149 | 0.786 |
| Age (years) | 1.041 | 0.949 to 1.142 | 0.396 |
| BMI (kg/m2) | 0.992 | 0.893 to 1.101 | 0.876 |
| WOMAC pain | 0.968 | 0.916 to 1.023 | 0.255 |
| Severe medial meniscal tear | 4.624 | 1.236 to 17.297 | 0.023 |
| Medial meniscal extrusion | 3.073 | 0.914 to 10.332 | 0.070 |
| BML medial plateau | 1.808 | 1.077 to 3.034 | 0.025 |
| JSW minimum (mm) | 0.752 | 0.518 to 1.093 | 0.136 |
| Variables, baseline value and 2-year change | |||
| Male | 1.679 | 0.533 to 5.285 | 0.376 |
| Age (years) | 1.066 | 0.982 to 1.158 | 0.128 |
| BMI (kg/m2), change at 2 years | 1.042 | 0.788 to 1.377 | 0.773 |
| WOMAC pain, change at 2 years | 1.022 | 0.998 to 1.045 | 0.069 |
| Severe medial meniscal tear, baseline | 5.351 | 1.543 to 18.629 | 0.008 |
| Medial meniscal extrusion, baseline | 3.894 | 1.230 to 12.326 | 0.021 |
| Medial compartment cartilage volume reduction of ≥8% at 2 years | 9.062 | 0.943 to 87.085 | 0.056 |
| JSW reduction of ≥7% at 2 years | 8.164 | 0.893 to 74.620 | 0.063 |
↵* Logistic regression to predict a knee (target) replacement.
BMI, body mass index; BML, bone marrow lesion; CI, confidence interval; JSW, joint space width; OR, odds ratio; WOMAC, Western Ontario and McMaster Universities osteoarthritis index.