Table 3

Association of summed synovitis scores from 11 sites with maximum score of five WOMAC pain items, assessed by ordinal logistic regression model

Knees with pain, n (%)Adjusted model,* OR (95% CI)
Max WOMAC score
Severity of synovitis (summed scores from 11 sites)Knees, N0 (no pain)1 (mild)2–4 (mod-ext)All subjects (N=400)Excluding subjects taking pain medicine (N=304)Subjects taking pain medicine (N=96)
Normal/equivocal (0–4)264130 (49)79 (30)55 (21)1.0 (ref)1.0 (ref)1.0 (ref)
Mild (5–8)7634 (45)25 (33)17 (22)0.8 (0.5 to 1.4)0.8 (0.4 to 1.5)1.2 (0.4 to 3.5)
Moderate (9–12)388 (21)14 (37)16 (42)2.8 (1.4 to 5.4)2.5 (1.2 to 5.4)5.4 (0.9 to 30.7)
Severe (≥13)222 (9)8 (36)12 (55)3.1 (1.2 to 7.9)2.7 (0.9 to 7.8)12.2 (1.2 to 121.1)
p Value for trend0.00760.0360.023
  • * Adjusted for age, sex, body mass index, radiographic osteoarthritis status, MRI bone marrow lesions and effusions.

  • ext, extreme; mod, moderate; ref, reference; WOMAC, Western Ontario and McMaster Osteoarthritis Index.