Table 1

The relationship between clinical scores of remission, imaging detected synovitis and quality of life outcomes

ACR remission
VariableNo (n=32)Yes (n=96)Test result, p value
Disease duration90 (72–132)96 (60–168)U=1467.5, p=0.705
SJC281 (0–1)0 (0–0)U=993.0, p<0.001
TJC281 (0–2)0 (0–0)U=730.0, p<0.001
CRP0.0 (0.0–3.8)0.0 (0.0–5.5)U=1365.0, p=0.273
HAQ0.64 (0.13–1.50)0.25 (0.00–0.97)U=1167.5, p=0.039
RAQoL4.0 (1.0–12.0)2.0 (0.0–7.8)U=1152.0, p=0.033
Total GS score4.5 (2.0–10.3)3.0 (1.0–5.8)U=1245.0, p=0.107
Total PD score1.0 (0.0–4.0)0.0 (0.0–2.0)U=1264.0, p=0.109
GS=0 and PD=0: n (%)4 (12.5)18 (18.8)χ2=0.66, p=0.417
GS≤1 and PD≤1: n (%)13 (40.6)59 (61.5)χ2=4.23, p=0.040
PD=0: n (%)13 (40.6)50 (52.1)χ2=1.26, p=0.262
PD≤1: n (%)20 (62.5)81 (84.4)χ2=6.90, p=0.009
Max PD n (%)=013 (40.6)50 (52.1)L×L χ2=3.26, p=0.071
17 (21.9)31 (32.3)
211 (34.4)11 (11.5)
31 (3.1)4 (4.2)
Joints PD n (%)=0180/224 (80.4)585/672 (87.1)NA
127/224 (12.1)66/672 (9.8)
216/224 (7.1)17/672 (2.5)
21/224 (0.4)4/672 (0.6)
SDAI remission
VariableNo (n=54)Yes (n=74)Test result, p value
Disease duration96 (72–138)90 (58–168)U=1899.0, p=0.632
SJC281 (0–3)0 (0–0)U=1077.0, p<0.001
TJC280 (0–1)0 (0–0)U=1330.0, p<0.001
CRP0.0 (0.0–6.3)0.0 (0.0–5.1)U=1965.5, p=0.846
HAQ0.56 (0.00–1.38)0.25 (0.00–0.87)U=1585.5, p=0.043
RAQoL4.0 (1.0–10.5)2.5 (0.0–6.3)U=1615.0, p=0.062
Total GS score4.0 (2.0–7.0)3.0 (1.0–6.0)U=1691.5, p=0.137
Total PD score1.0 (0.0–2.0)0.0 (0.0–2.0)U=1831.5, p=0.389
GS=0 and PD=0: n (%)5 (9.3)17 (23.0)χ2=4.13, p=0.042
GS≤1 and PD≤1: n (%)28 (51.9)44 (59.5)χ2=0.73, p=0.392
PD=0: n (%)23 (42.6)40 (54.1)χ2=1.64, p=0.200
PD≤1: n (%)41 (75.9)60 (81.1)χ2=0.50, p=0.480
Max PD n (%)=023 (42.6)40 (54.1)L×L χ2=1.08, p=0.300
118 (33.3)20 (27.0)
211 (20.4)11 (14.9)
32 (3.7)3 (4.1)
Joints PD n (%)=0323/378 (85.4)442/518 (85.3)NA
138/378 (10.1)55/518 (10.6)
215/378 (4.0)18/518 (3.5)
32/378 (0.5)3/518 (0.6)
2010 ACR/EULAR remission
VariableNo (n=99)Yes (n=29)Test result, p value
Disease duration96 (60–132)96 (60–186)U=1365.5, p=0.689
HAQ0.38 (0.00–1.13)0.25 (0.00–0.56)U=1127.0, p=0.074
RAQoL3 (1–9)1 (0–4)U=973.0, p=0.008
Total GS score3.0 (2.0–6.0)3.0 (1.0–10.0)U=1363.0, p=0.678
Total PD score1.0 (1.0–2.0)1.0 (0.0–2.5)U=1345.5, p=0.583
GS=0 and PD=0: n (%)16 (16.2)6 (20.7)χ2=0.32, p=0.570
GS≤1 and PD≤1: n (%)57 (57.6)15 (51.7)χ2=0.32, p=0.576
PD=0: n (%)49 (49.5)14 (48.3)χ2=0.01, p=0.908
PD≤1: n (%)79 (79.8)22 (75.9)χ2=0.21, p=0.648
Max PD n (%)=049 (49.5)14 (48.3)L×L χ2=0.53, p=0.466
130 (30.3)8 (27.6)
218 (18.2)4 (13.8)
32 (2.0)3 (10.3)
Joints PD n (%)=0599/693 (86.4)166/203 (81.8)NA
168/693 (9.8)25/2203 (12.3)
224/693 (3.5)9/203 (4.3)
32/693 (0.3)3/203 (1.5)
  • Values are median (first–third quartile) unless otherwise indicated.

  • ACR rem; American College of Rheumatology remission criteria; CRP, C-reactive protein; GS, grey scale synovitis; HAQ, health assessment questionnaire score; L×L, linear by linear test of association; Max PD, maximum power Doppler score observed in any joint; PD, power Doppler signal; RAQoL, rheumatoid arthritis quality of life score; SJC, swollen joint count; TJC, tender joint count; U, Mann–Whitney U test.