Adjusted generalised estimating equation Poisson analysis for infections requiring hospitalisation
| CDAI (N=6020) | DAS28 (N=3666) | |||||
|---|---|---|---|---|---|---|
| Estimated IRR | 95% CI | p Value | Estimated IRR | 95% CI | p Value | |
| 5-Unit change in CDAI | ||||||
| If CDAI <10 | 1.56 | 0.94 to 2.59 | 0.08 | – | – | – |
| If CDAI ≥10† | 1.03 | 0.86 to 1.22 | NS | – | – | – |
| DAS28 (0.6 units) | – | – | – | 1.25 | 1.03 to 1.51 | 0.03 |
| No prednisone use‡ | 1 | – | – | 1 | – | – |
| Prednisone <7.5 mg daily | 1.31 | 0.64 to 2.66 | NS | 1.42 | 0.38 to 5.25 | NS |
| Prednisone ≥7.5 mg daily | 6.47 | 3.10 to 13.50 | <0.001 | 12.78 | 4.14 to 39.48 | <0.001 |
| History of infections | 2.41 | 1.24 to 4.70 | 0.01 | – | – | – |
| History of hospitalised infections | 7.17 | 3.33 to 15.45 | <0.001 | – | – | – |