Table 2

Results of linear random effects analysis: mean difference in HAQ score over time by parity and association between HAQ score and latency

AdjustmentParous vs nulliparous (95% CI)Change in HAQ score by latency (95% CI)
Age at symptom onset, symptom duration−0.19 (−0.32 to −0.06)*0.06 (0.02 to 0.10)*
As above plus SES, smoking history, RF status, ACPA status, comorbidity and satisfaction of ACR criteria for RA−0.19 (−0.34 to −0.05)*0.05 (0.002 to 0.09)*
  • Change in HAQ score by latency is per decade increase in latency.

  • Comorbidity is number of patient-reported comorbid conditions (by ICD-10 chapter).

  • Patients with RA met the 1987 ACR criteria for RA at least once during follow-up.

  • * Significant difference/change.

  • ACPA, anticitrullinated peptide antibodies; HAQ, Health Assessment Questionnaire; RF, rheumatoid factor; SES, socioeconomic status by occupation; smoking history at baseline (ever smoked vs never smoked).