Table 2

Radiographic evolution of the Leuven patient population

Leuven observational cohortLeuven RCT
ICTS (n=37)IMT (n=43)Total (n=80)(n=20)
RRP (%)1 (2.7)4 (9.3)5 (6.3)2 (10)
Mean (SD) change in erosions–0.81 (1.74)0.43 (2.52)0.19 (2.19)0.62 (1.39)
Mean (SD) change in JSN–0.14 (1.41)0.73 (2.63)0.39 (2.17)0.52 (1.02)
Mean (SD) change in tSHS–0.95 (2.83)1.16 (4.11)0.58 (3.61)1.15 (2.22)
  • ICTS, initial combination therapy with steroid; IMT, initial disease-modifying antirheumatic drug monotherapy; JSN, joint space narrowing; RCT, randomised controlled trial; RRP, rapid radiographic progression; tSHS, total modified Sharp/van der Heijde score.