Sum | MAF | Genotype frequency test (dominant model) | ||||
---|---|---|---|---|---|---|
Case | Contol | Case | Contol | OR | p Value | |
rs11203367 | ||||||
All | 646 | 385 | 0.44 | 0.42 | 1.19 (0.90 to 1.56) | 0.2 |
Men | 218 | 180 | 0.47 | 0.40 | 1.49 (0.96 to 2.33) | 0.063 |
Women | 398 | 188 | 0.42 | 0.43 | 1.06 (0.73 to 1.56) | 0.7 |
Ever-smoker | 174 | 385 | 0.43 | 0.42 | 1.14 (0.76 to 1.70) | 0.5 |
Never-smoker | 178 | 385 | 0.45 | 0.42 | 1.06 (0.72 to 1.57) | 0.7 |
Male ever-smoker | 76 | 180 | 0.45 | 0.40 | 1.46 (0.78 to 2.71) | 0.2 |
Male never-smoker | 40 | 180 | 0.53 | 0.40 | 1.38 (0.62 to 3.10) | 0.4 |
Female ever-smoker | 98 | 188 | 0.41 | 0.43 | 0.99 (0.58 to 1.72) | 0.9 |
Female never-smoker | 138 | 188 | 0.43 | 0.43 | 0.99 (0.61 to 1.61) | 0.9 |
rs1748033 | ||||||
All | 635 | 391 | 0.34 | 0.30 | 1.32 (1.02 to 1.72) | 0.03 |
Men | 215 | 183 | 0.35 | 0.28 | 1.36 (0.90 to 2.06) | 0.13 |
Women | 389 | 191 | 0.32 | 0.31 | 1.33 (0.93 to 1.91) | 0.11 |
Ever-smoker | 158 | 391 | 0.36 | 0.30 | 1.56 (1.06 to 2.31) | 0.02 |
Never-smoker | 178 | 391 | 0.31 | 0.30 | 1.06 (0.73 to 1.53) | 0.7 |
Male ever-smoker | 70 | 183 | 0.38 | 0.28 | 1.79 (0.98 to 3.27) | 0.043 |
Male never-smoker | 41 | 183 | 0.35 | 0.28 | 1.35 (0.65 to 2.82) | 0.4 |
Female ever-smoker | 88 | 191 | 0.34 | 0.31 | 1.48 (0.86 to 2.55) | 0.13 |
Female never-smoker | 137 | 191 | 0.30 | 0.31 | 1.03 (0.65 to 1.64) | 0.9 |
↵* rs112033673 (T/C, T is the minor allele) and rs174803 (T/C, T is the minor allele) were genotyped for the test. Only case subjects were stratified with smoking status.
MAF, minor allele frequency; PADI4, peptidyl arginine deiminase 4; RA, rheumatoid arthritis.