Table 3

Echocardiography at follow-up in patients with juvenile dermatomyositis (JDM) and controls

nPatients with JDMControlsp Value
Two-dimensional echocardiography
 LA area, cm25915.5 (3.4)16.5 (3.7)0.095
 RA area, cm25913.3 (3.1)14.2 (3.5)0.086
 LV ejection fraction, %4763.2 (5.1)62.5 (5.5)0.487
 LV diastolic volume, cm34791.0 (25.4)97.5 (25.7)0.029
 LV systolic volume, cm34733.8 (11.6)37.1 (12.5)0.051
M-mode echocardiography
 Septal diastolic thickness, mm597.9 (1.7)7.8 (1.5)0.643
 Septal systolic thickness, mm5910.9 (2.3)10.7 (2.0)0.537
 LV diastolic diameter, mm5948.1 (5.4)49.5 (5.9)0.073
 LV systolic diameter, mm5931.6 (4.8)32.8 (4.7)0.047
 PW diastolic thickness, mm598.3 (1.6)7.9 (1.4)0.858
 PW systolic thickness, mm5912.7 (3.1)12.4 (2.4)0.381
Conventional Doppler
 E velocity, m/s590.86 (0.17)0.86 (0.15)0.858
 A velocity, m/s590.49 (0.11)0.47 (0.10)0.132
 E/A ratio591.81 (0.50)1.95 (0.54)0.116
 MV deceleration time, ms59193 (42)200 (42)0.278
 LVOT stroke volume, ml5659 (21.4)67 (18.9)0.008
 LVOT cardiac output, litres/min554.1 (1.22)4.5 (1.20)0.021
Valvular heart disease*
 Mitral regurgitation592 (3)2 (3)NS
 Aortic regurgitation592 (3)1 (2)NS
Tissue Doppler
 E' velocity, cm/s5611.3 (2.8)12.4 (2.1)0.003
 E/E' ratio568.04 (2.30)7.09 (1.20)0.007
  • Values are mean (SD). n=47 is due to difficulties with data acquisition when measuring ejection fraction. n=55 and 56 is due to missing Doppler data in 3–4 of the pairs.

  • * Number (%) with ≥ grade 1 regurgitation.

  • A, late diastolic transmitral flow; E, early diastolic transmitral flow; E', early diastolic tissue velocity; LA, left atrium; LV, left ventricle; LVOT, left ventricular outflow tract; MV, mitral valve; n, number of pairs; PW, posterior wall; RA, right atrium.