n | Patients with JDM | Controls | p Value | |
---|---|---|---|---|
Two-dimensional echocardiography | ||||
LA area, cm2 | 59 | 15.5 (3.4) | 16.5 (3.7) | 0.095 |
RA area, cm2 | 59 | 13.3 (3.1) | 14.2 (3.5) | 0.086 |
LV ejection fraction, % | 47 | 63.2 (5.1) | 62.5 (5.5) | 0.487 |
LV diastolic volume, cm3 | 47 | 91.0 (25.4) | 97.5 (25.7) | 0.029 |
LV systolic volume, cm3 | 47 | 33.8 (11.6) | 37.1 (12.5) | 0.051 |
M-mode echocardiography | ||||
Septal diastolic thickness, mm | 59 | 7.9 (1.7) | 7.8 (1.5) | 0.643 |
Septal systolic thickness, mm | 59 | 10.9 (2.3) | 10.7 (2.0) | 0.537 |
LV diastolic diameter, mm | 59 | 48.1 (5.4) | 49.5 (5.9) | 0.073 |
LV systolic diameter, mm | 59 | 31.6 (4.8) | 32.8 (4.7) | 0.047 |
PW diastolic thickness, mm | 59 | 8.3 (1.6) | 7.9 (1.4) | 0.858 |
PW systolic thickness, mm | 59 | 12.7 (3.1) | 12.4 (2.4) | 0.381 |
Conventional Doppler | ||||
E velocity, m/s | 59 | 0.86 (0.17) | 0.86 (0.15) | 0.858 |
A velocity, m/s | 59 | 0.49 (0.11) | 0.47 (0.10) | 0.132 |
E/A ratio | 59 | 1.81 (0.50) | 1.95 (0.54) | 0.116 |
MV deceleration time, ms | 59 | 193 (42) | 200 (42) | 0.278 |
LVOT stroke volume, ml | 56 | 59 (21.4) | 67 (18.9) | 0.008 |
LVOT cardiac output, litres/min | 55 | 4.1 (1.22) | 4.5 (1.20) | 0.021 |
Valvular heart disease* | ||||
Mitral regurgitation | 59 | 2 (3) | 2 (3) | NS |
Aortic regurgitation | 59 | 2 (3) | 1 (2) | NS |
Tissue Doppler | ||||
E' velocity, cm/s | 56 | 11.3 (2.8) | 12.4 (2.1) | 0.003 |
E/E' ratio | 56 | 8.04 (2.30) | 7.09 (1.20) | 0.007 |
Values are mean (SD). n=47 is due to difficulties with data acquisition when measuring ejection fraction. n=55 and 56 is due to missing Doppler data in 3–4 of the pairs.
↵* Number (%) with ≥ grade 1 regurgitation.
A, late diastolic transmitral flow; E, early diastolic transmitral flow; E', early diastolic tissue velocity; LA, left atrium; LV, left ventricle; LVOT, left ventricular outflow tract; MV, mitral valve; n, number of pairs; PW, posterior wall; RA, right atrium.