Mean systemic lupus erythematosus disease activity index (SLEDAI) by group and period
| Group | Mean (range) SLEDAI before randomisation | Mean (range) SLEDAI after randomisation | Change | p Value for change | Difference in change between groups | p Value for difference between groups |
|---|---|---|---|---|---|---|
| SLEDAI | ||||||
| Atorvastatin | 2.0 (0–18) | 2.2 (0–24) | 0.2 | 0.45* | 0.1 | 0.92* |
| Placebo | 1.9 (0–14) | 2.0 (0–18) | 0.1 | 0.54* | ||
| PGA | ||||||
| Atorvastatin | 0.63 (0–3) | 0.72 (0–3) | 0.09 | 0.034* | 0.09 | 0.19* |
| Placebo | 0.68 (0–3) | 0.67 (0–3) | 0.00 | 0.81* | ||
↵* Based on a mixed-effects model to account for repeated measures of SLEDAI on the same patients.
PGA, Physician Global Assessment.