Changes in indicators of atherosclerosis
| Measure | Mean at baseline | Mean after 2 years | Mean change | p Value for change | Difference in change, statin minus placebo(95% CI) | p Value for difference between groups* |
|---|---|---|---|---|---|---|
| Loge (coronary artery calcium score + 1) | ||||||
| Atorvastatin | 1.16 | 1.24 | 0.08 | 0.52 | −0.08 (−0.39 to 0.23) | 0.62 |
| Placebo | 1.19 | 1.35 | 0.15 | 0.16 | ||
| Carotid intima media thickness (mm) | ||||||
| Atorvastatin | 0.59 | 0.66 | 0.07 | <0.0001 | −0.02 (−0.05 to 0.01) | 0.24 |
| Placebo | 0.57 | 0.66 | 0.09 | <0.0001 | ||
This table is based on the 96 patients given atorvastatin and the 91 patients given placebo for whom there were both baseline and follow-up measures.
↵* Based on an ANCOVA model controlling for baseline level.