Table 5

Patient acceptable symptom state (PASS) and minimal clinically important improvement (MCII) scores for global state and functional state in patients with knee or hip OA

Global PASS(95% CI)Global MCII(95% CI)Function PASS(95% CI)Function MCII(95% CI)
Knee OA
 Patient NRS (0–10)3.33 (3.17 to 3.48)−2.72 (−2.92 to −2.51)3.30 (3.16 to 3.45)−2.79 (−3.01 to −2.57)
 Physician NRS (0–10)3.07 (2.94 to 3.21)−2.50 (−2.68 to −2.32)3.03 (2.90 to 3.16)−2.55 (−2.73 to −2.38)
 WOMAC function (0–100)28.06 (25.74 to 30.38)−17.13 (−20.07 to −14.19)28.40 (26.03 to 30.78)−17.02 (−20.15 to −13.90)
Hip OA
 Patient NRS (0–10)3.44 (3.16 to 3.72)−2.47 (−2.84 to −2.10)3.40 (3.13 to 3.68)−2.51 (−2.91 to −2.11)
 Physician NRS (0–10)3.30 (3.04 to 3.57)−2.29 (−2.62 to −1.97)3.33 (3.07 to 3.59)−2.25 (−2.57 to −1.93)
 WOMAC function (0–100)32.55 (28.70 to 36.40)−14.17 (−19.18 to −9.15)33.41 (29.53 to 37.29)−13.34 (−18.51 to −8.18)
  • Global PASS is defined as the value of the measurement beyond which patients consider their global state as satisfactory.

  • Global MCII is defined as the smallest change in global state that signifies an important improvement in a patient's symptoms.

  • Function PASS is defined as the value of the measurement beyond which patients consider their functional state as satisfactory.

  • Function MCII is defined as the smallest change in functional state that signifies an important improvement in a patient's symptoms.

  • MCII, minimal clinically important improvement; NRS, numerical rating scale; OA, osteoarthritis; PASS, patient acceptable symptomatic state; WOMAC, Western Ontario and McMaster Universities osteoarthritis index.