Table 1

Variables selected by consensus (≥80%) during second round of the Delphi survey

CAPS
VariablesFMF (%)TRAPS (%)MKD (%)FCAS (%)MWS (%)NOMID (%)
Fatigue8281878782
Number of days of illness in the past 3 months9488100938782
Intensity of attacks8981
Arthritis100
Arthralgia878087
Measure of joint damage94
Presence absence of skin rash94818210010088
Intensity of skin rash938788
Frequency of skin rash8780
Number of days with skin rash in a month939382
Chest symptoms94
Muscle symptoms82
Gastrointestinal symptoms100
Painful lymphnodes94
Hearing loss9382
Eye symptoms82
Headaches82
Brain MRI82
Cognitive function test94
Funduscopy88
Limitation of daily activity8987878081
Days of school /work loss8381
Global DAS physician838188
Global DAS patient82
ESR83
  • New variables/items suggested by experts after the first round are shown in italics.

  • CAPS, cryopyrin-associated periodic syndromes; CINCA/NOMID, chronic infantile neurological, cutaneous, articular/neonatal onset multisystem inflammatory disease; DAS, Disease Activity Score; ESR, erythrocyte sedimentation rate; FCAS, familial cold autoinflammatory syndrome; FMF, familial Mediterranean fever; MKD, mevalonate kinase deficiency; MWS, Muckle-Wells syndrome; TRAPS, TNF receptor-1-associated periodic syndrome.