ASDAS | BASDAI | CRP | ||||
---|---|---|---|---|---|---|
Baseline (n=56) | Change (n=47) | Baseline (n=60) | Change (n=53) | Baseline (n=60) | Change (n=53) | |
BASDAI (0–100) | 0.75*** | 0.76*** | – | – | 0.22 | 0.44** |
BASFI (0–100) | 0.46*** | 0.65*** | 0.68*** | 0.62*** | 0.39 | 0.37** |
BASMI (0–100) | 0.23 | 0.48** | 0.24 | 0.45** | 0.18 | 0.38** |
Pain (0–100 mm) | 0.71*** | 0.75*** | 0.75*** | 0.76*** | 0.20 | 0.43** |
Fatigue (0–100 mm) | 0.41** | 0.61*** | 0.71*** | 0.88*** | 0.12 | 0.37** |
Patient's global (0–100 mm) | 0.66*** | 0.76*** | 0.74*** | 0.78*** | 0.08 | 0.39** |
Physician's global (0–100 mm) | 0.63*** | 0.70*** | 0.57*** | 0.46** | 0.32* | 0.50*** |
Swollen joint count (0–28) | 0.21 | 0.16 | 0.26 | 0.32* | 0.15 | 0.15 |
Tender joint count (0–28) | 0.06 | 0.21 | 0.38** | 0.37** | −0.09 | −0.02 |
MASES (0–13) | 0.21 | 0.03 | 0.39** | 0.21 | −0.09 | −0.02 |
Serum CRP (mg/l) | 0.73*** | 0.79*** | 0.22 | 0.44** | – | – |
Berlin MRI SIJ IS (0–32) | −0.14 | 0.46** | −0.23 | 0.31 | 0.06 | 0.27 |
Berlin MRI lumbar spine IS (0–27) | −0.30* | 0.22 | −0.41** | −0.05 | 0.05 | 0.25 |
Berlin MRI total IS (0–47) | −0.26 | 0.34* | −0.31* | 0.06 | 0.02 | 0.21 |
Berlin MRI SIJ CS (0–8) | 0.19 | −0.03 | 0.07 | 0.09 | 0.17 | 0.02 |
Spearman rank correlation coefficients:
↵* p<0.05;
↵** p<0.01;
↵*** p<0.001.
ASDAS could not be calculated in four patients at baseline and in five patients at week 22. Seven patients were excluded before week 22.
ASDAS, Ankylosing Spondylitis Disease Activity Score; BASDAI, Bath Ankylosing Spondylitis Disease Activity Index; BASFI, Bath Ankylosing Spondylitis Functional Index; BASMI, Bath Ankylosing Spondylitis Metrology Index; CRP, C-reactive protein; CS, chronicity score; IS, inflammation score; MASES, Maastricht Ankylosing Spondylitis Enthesitis Score; SIJ, sacroiliac joints.