Table 3

Correlation between ASDAS, BASDAI, serum CRP and clinical, biochemical and experimental imaging measures of disease activity at baseline and between changes in these parameters from week 0 to 22

ASDASBASDAICRP
Baseline (n=56)Change (n=47)Baseline (n=60)Change (n=53)Baseline (n=60)Change (n=53)
BASDAI (0–100)0.75***0.76***0.220.44**
BASFI (0–100)0.46***0.65***0.68***0.62***0.390.37**
BASMI (0–100)0.230.48**0.240.45**0.180.38**
Pain (0–100 mm)0.71***0.75***0.75***0.76***0.200.43**
Fatigue (0–100 mm)0.41**0.61***0.71***0.88***0.120.37**
Patient's global (0–100 mm)0.66***0.76***0.74***0.78***0.080.39**
Physician's global (0–100 mm)0.63***0.70***0.57***0.46**0.32*0.50***
Swollen joint count (0–28)0.210.160.260.32*0.150.15
Tender joint count (0–28)0.060.210.38**0.37**−0.09−0.02
MASES (0–13)0.210.030.39**0.21−0.09−0.02
Serum CRP (mg/l)0.73***0.79***0.220.44**
Berlin MRI SIJ IS (0–32)−0.140.46**−0.230.310.060.27
Berlin MRI lumbar spine IS (0–27)−0.30*0.22−0.41**−0.050.050.25
Berlin MRI total IS (0–47)−0.260.34*−0.31*0.060.020.21
Berlin MRI SIJ CS (0–8)0.19−0.030.070.090.170.02
  • Spearman rank correlation coefficients:

  • * p<0.05;

  • ** p<0.01;

  • *** p<0.001.

  • ASDAS could not be calculated in four patients at baseline and in five patients at week 22. Seven patients were excluded before week 22.

  • ASDAS, Ankylosing Spondylitis Disease Activity Score; BASDAI, Bath Ankylosing Spondylitis Disease Activity Index; BASFI, Bath Ankylosing Spondylitis Functional Index; BASMI, Bath Ankylosing Spondylitis Metrology Index; CRP, C-reactive protein; CS, chronicity score; IS, inflammation score; MASES, Maastricht Ankylosing Spondylitis Enthesitis Score; SIJ, sacroiliac joints.