ASDAS scores at inclusion and changes in ASDAS from inclusion to week 22 stratified according to different patient characteristics
| Median (IQR) ASDAS at week 0 (n=56) | p Value | Median (IQR) change in ASDAS from week 0 to 22 (n=47) | p Value | |
|---|---|---|---|---|
| BASDAI <40 mm | 2.79 (2.23–3.85) | 1.08 (0.93–2.41) | ||
| BASDAI ≥40 mm | 4.07 (3.26–4.71) | 0.004 | 2.13 (1.07–2.91) | 0.29 |
| Serum CRP ≤8 mg/l | 2.87 (2.54–3.34) | 0.99 (0.87–1.17) | ||
| Serum CRP >8 mg/l | 4.15 (3.30–4.71) | 0.001 | 2.19 (1.13–3.23) | 0.006 |
| No peripheral arthritis | 3.72 (2.97–4.37) | 1.58 (0.90–2.55) | ||
| Peripheral arthritis | 4.22 (3.72–5.24) | 0.12 | 3.01 (1.37–4.12) | 0.03 |
| No psoriatic arthritis | 3.77 (2.99–4.45) | 2.06 (0.95–2.91) | ||
| Psoriatic arthritis | 4.26 (3.09–4.62) | 0.39 | 1.36 (0.99–2.73) | 0.68 |
| Berlin MRI SIJ IS score 0 | 4.60 (3.45–4.91) | 1.94 (1.29–3.45) | ||
| Berlin MRI SIJ IS score ≥1 | 3.78 (2.98–4.36) | 0.09 | 1.80 (0.90–2.91) | 0.30 |
| Berlin MRI total IS score 0 | 4.71 (3.15–5.23) | 2.38 (1.32–4.30) | ||
| Berlin MRI total IS score ≥1 | 3.69 (2.98–2.22) | 0.03 | 1.58 (0.97–2.90) | 0.16 |
| Non-responders at week 22 | 2.99 (2.81–3.78) | 0.90 (0.49–1.36) | ||
| Responders at week 22 | 4.15 (3.63–4.78) | 0.008 | 2.50 (1.47–3.32) | 0.003 |
ASDAS could not be calculated in four patients at baseline and in five patients at week 22. Seven patients were excluded before week 22.
ASDAS, Ankylosing Spondylitis Disease Activity Score; BASDAI, Bath Ankylosing Spondylitis Disease Activity Index; CRP, C-reactive protein; IS, inflammation score; SIJ, sacroiliac joints.