Factors associated with developing a CBOE score greater than 7 on multivariable analysis using logistic regression
| Factor | Odds ratio (95% CI) | p Value |
|---|---|---|
| eGFR | 1.4 (1.2 to 1.6)* | 0.0001 |
| Age | 0.8 (0.6 to 0.9)† | 0.04 |
| Albumin | 1.04 (1.0 to 1.1)‡ | 0.05 |
| Gender | 1.4 (0.7 to 2.4)§ | 0.33 |
| Relapse rate | 0.1 (0.001 to 200) | 0.58 |
| Vasculitis type | 0.70 | |
| MPA | 0.8 (0.3 to 2.3) | |
| Renal limited | 0.7 (0.2 to 2.1) | |
| Requirement for plasma exchange | 0.8 (0.4 to 1.7) | 0.60 |
| BVAS | 1.0 (0.9 to 1.0)** | 0.62 |
| CRP | 1.0 (0.9 to 1.0)†† | 0.76 |
There was no co-linearity (>0.7) observed between the predictor factors.
↵* For every 10-point fall in estimated glomerular filtration rate (eGFR);
↵† For every decade decrease;
↵‡ For every 1-point fall in albumin;
↵§ Male versus female;
¶ Relative to Wegener's granulomatosis;
↵** For every point increase;
↵†† For every 10-point rise in C-reactive protein (CRP).
BVAS, Birmingham vasculitis activity score; CBOE, combined burden of events; MPA, microscopic polyangiitis.