RR for AMI, non-fatal and fatal AMI according to history of gout, stratified by gender
| Women | Men | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| No of AMI | Incidence (per 1000 PY) | Crude RR (95% CI) | Multivariate RR* (95% CI) | No of AMI | Incidence (per 1000 PY) | Crude RR (95% CI) | Multivariate RR* (95% CI) | p Value for interaction by gender | |
| All AMI | |||||||||
| No gout | 752 | 6.03 | 1.0 (referent) | 1.0 (referent) | 1837 | 10.34 | 1.0 (referent) | 1.0 (referent) | 0.003 |
| Gout | 244 | 10.04 | 1.67 (1.45 to 1.93) | 1.39 (1.20 to 1.61) | 435 | 12.23 | 1.19 (1.07 to 1.32) | 1.11 (0.99 to 1.23) | |
| Non-fatal AMI | |||||||||
| No gout | 552 | 4.42 | 1.0 (referent) | 1.0 (referent) | 1420 | 7.99 | 1.0 (referent) | 1.0 (referent) | 0.005 |
| Gout | 183 | 7.53 | 1.71 (1.44 to 2.02) | 1.41 (1.19 to 1.67) | 335 | 9.42 | 1.18 (1.05 to 1.33) | 1.11 (0.98 to 1.25) | |
| Fatal AMI | |||||||||
| No gout | 200 | 1.60 | 1.0 (referent) | 1.0 (referent) | 417 | 2.35 | 1.0 (referent) | 1.0 (referent) | 0.30 |
| Gout | 61 | 2.51 | 1.57 (1.18 to 2.09) | 1.33 (0.99 to 1.78) | 100 | 2.81 | 1.19 (0.96 to 1.49) | 1.10 (0.88 to 1.38) | |
↵* Multivariate models were adjusted for age (continuous), baseline history of comorbid medical condition (hypertension, diabetes, hyperlipidaemia and chronic obstructive pulmonary disease) (yes, no), baseline Charlson comorbidity score (continuous) and monthly prescription drug use (non-steroidal anti-inflammatory drug, diuretic, statin, anticoagulant, aspirin, hormone replacement therapy and glucocorticoid) (yes, no) as time-varying covariates.
AMI, acute myocardial infarction; PY, person-years; RR, relative risk.